HCS Analyzer

Designed for those interested in genetics, HCS Analyzer is a software application that helps you analyze and process multivariate data with the aid of High Content Screening (HCS).

.NET Framework must be installed on the PC before running this tool. Its interface is based on a large window with separate areas dedicated to data visualization, statistics and analysis, genomic analysis, and plugins.

It's possible to import screens from CSV or TXT files, display classes, view the entire screening, current plate or plate by plate, as well as select the active class and QC.

Settings can be configured when it comes to dimensionality reduction, such as PCA or Greedy Stepwise unsupervised, or InfoGain, OneR or Greedy supervised. It's possible to correct errors systematically using a B-score or Diffusion Model approach, as well as Z-Factor rejection with a custom-defined threshold, negative and positive control.

The normalization mode can be chosen between percent of control, normalized percent inhibition, Z-score, and minimum/maximum mode. Additional customization can be made for the classification level. HCS Analyzer lets you generate univariate or multivariate screens, single-cell simulators, or screens from images.

Plus, you can copy values and properties to the Clipboard, swap classes, create new images or 3D worlds, as well as pick the correlation matrix type (Pearson, Spearman, MIC). These are just part of the configuration settings provided by this tool. It's currently in beta development stage.