MoveOnBoot allows you to copy, moves or delete files on the next system boot. This comes in very handy, if you need to replace or delete files which are locked by other applications, loaded into memory or cannot be changed until next system boot.

You could manually enter a line to the wininit files, but using MoveOnBoot is much simpler, since the program can be integrated into shell - it creates the "Copy/Move/Delete on boot" context menu item.