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MedCalc Changelog

What's new in MedCalc 22.021

Feb 21, 2024
  • Fixed a problem in the legend for scatter diagram in case a trendline and subgroups were selected.
  • Some minor bugs fixes.

New in MedCalc 22.020 (Feb 14, 2024)

  • Fixed some minor bugs.

New in MedCalc 22.018 (Jan 16, 2024)

  • Fixed a bug in the display of the result of the D'Agostino-Pearson test for normal distribution Create summary statistics table.

New in MedCalc 22.016 (Nov 15, 2023)

  • New: Waterfall charts

New in MedCalc 22.013 (Sep 18, 2023)

  • New: Comparison of trimmed means of paired samples
  • New: Yuen-Welch test for the comparison of 2 independent trimmed means.
  • Computional notes are given on Calculation of Trimmed Mean, SE and confidence interval
  • Revision of the definition of "percentage trimmed":
  • In previous MedCalc versions, for a 20% trimming, the program would trim 10% at the lower tail and 10% at the higher tail, so 20% in total. This was in agreement with Excel
  • In the new MedCalc version, for a 20% trimming, the program trims 20% at the lower tail and 20% at the higher tail, so 40% in total. This is in agreement with SPSS, R and other major statistical packages.
  • For the summary statistics report, when recalling older analyses, MedCalc will adapt the % value of the trimmed mean. When you selected a 20% trimmed mean in the old version, the report will show that this is now called a 10% trimmed mean. The reported trimmed mean will remain the same. For new analyses, the new definition will be applied automatically.
  • For the trimmed mean spreadsheet functions there will be no conversion and the calculated trimmed mean will always be that corresponding to the revised definition. The calculated trimmed mean will be different.
  • Fixed a bug that could cause the program to produce an error when using MedCalc Help in the Help menu.

New in MedCalc 22.012 (Sep 15, 2023)

  • New: Comparison of trimmed means of paired samples
  • New: Yuen-Welch test for the comparison of 2 independent trimmed means.
  • Computional notes are given on Calculation of Trimmed Mean, SE and confidence interval
  • Revision of the definition of "percentage trimmed":
  • In previous MedCalc versions, for a 20% trimming, the program would trim 10% at the lower tail and 10% at the higher tail, so 20% in total. This was in agreement with Excel
  • In the new MedCalc version, for a 20% trimming, the program trims 20% at the lower tail and 20% at the higher tail, so 40% in total. This is in agreement with SPSS, R and other major statistical packages.
  • For the summary statistics report, when recalling older analyses, MedCalc will adapt the % value of the trimmed mean. When you selected a 20% trimmed mean in the old version, the report will show that this is now called a 10% trimmed mean. The reported trimmed mean will remain the same. For new analyses, the new definition will be applied automatically.
  • For the trimmed mean spreadsheet functions there will be no conversion and the calculated trimmed mean will always be that corresponding to the revised definition. The calculated trimmed mean will be different.

New in MedCalc 22.007 (Jun 17, 2023)

  • Fixed a bug that caused text not to be displayed correctly in graph text boxes.

New in MedCalc 22.001 (May 12, 2023)

  • Version 22 introduces a new file format. The new format is faster and lighter. Important: files saved in MedCalc version 21 cannot be read by previous MedCalc versions. Files saved in all previous MedCalc versions can be read by this version; but when saved, the new file format is used.
  • New: Scripts
  • New spreadsheet functions EVAL, FREQUENCY, VFREQUENCY, DEVSQ, VDEVSQ, INTERCEPT, VINTERCEPT, STEYX, VSTEYX, TESTNORM and VTESTNORM.
  • Redefined the CELL function.
  • Fixed a bug in Case control matching when saving the matched data to a new file.
  • In Diagnostic test (2x2 table): when predictive value is 0 or 100%, a Clopper-Pearson confidence interval is reported.
  • New operators ! (Not), && (And), || (Or)
  • The operator != can be used as an alternative to the <> (Not equal) comparison operator. E.g. 5!=1 is true.

New in MedCalc 20.305 (Apr 27, 2023)

  • Fixed a bug in Case control matching when saving the matched data to a new file.
  • In Diagnostic test (2x2 table): when the predictive value is 0 or 100%, a Clopper-Pearson confidence interval is reported.

New in MedCalc 20.218 (Feb 11, 2023)

  • Fixed a problem with the display of the Diagnostic test dialog box.

New in MedCalc 20.217 (Feb 9, 2023)

  • In Frequency tables (Chi-squared test) and Fisher's exact test, moved the option to show all percentages from the results window to the dialog box. This fixes a problem with copying-pasting results to other programs.
  • Fixed a bug in the Categorize function, which could cause the function to always return the default value.
  • Fixed a problem with multiple monitors.

New in MedCalc 20.216 (Feb 5, 2023)

  • In Frequency tables (Chi-squared test) and Fisher's exact test, moved the option to show all percentages from the results window to the dialog box. This fixes a problem with copying-pasting results to other programs.
  • Fixed a bug in the Categorize function, which could cause the function to always return the default value.
  • Fixed a problem with multiple monitors.

New in MedCalc 20.215 (Jan 21, 2023)

  • In Frequency tables (Chi-squared test) and Fisher's exact test, moved the option to show all percentages from the results window to the dialog box. This fixes a problem with copying-pasting results to other programs.
  • Fixed a bug in the Categorize function, which could cause the function to always return the default value.
  • Fixed a problem with multiple monitors.

New in MedCalc 20.214 (Jan 17, 2023)

  • In Frequency tables (Chi-squared test) and Fisher's exact test, moved the option to show all percentages from the results window to the dialog box. This fixes a problem with copying-pasting results to other programs.
  • Fixed a bug in the Categorize function, which could cause the function to always return the default value.
  • Fixed a problem with multiple monitors.

New in MedCalc 20.211 (Jan 4, 2023)

  • Some improvements for high resolution screens and minor user-interface changes.

New in MedCalc 20.210 (Dec 22, 2022)

  • Corrected a bug that could cause failure of saving & recalling tables.
  • Fixed a problem in Reference interval estimation when Box-cox transformation was applied in the Robust method. In some datasets, the values for upper and lower value of the CI of the upper limit were swapped and a missing value was represented by a 0.

New in MedCalc 20.2 (Dec 8, 2022)

  • Added several new options for Correlogram and Correlation table.
  • Changed the methodology of the calculation of the P-value in the Mann-Whitney test, the Signed rank sum test and paired samples Wilcoxon test. In these tests, when an exact P-value can be calculated, the program will also report the Normal approximation method P-value in a footnote below the table.
  • Changed some more visual aspects of windows and dialog boxes (mainly corrections of low contrast issues in Windows 11).
  • Corrected a problem that caused the file selector box to remain hidden behind the MedCalc main window when printing to a file or PDF.
  • Corrected a problem that could fail a logical expression when data were missing.

New in MedCalc 20.123 (Dec 2, 2022)

  • Changed the methodology of the calculation of the exact P-value in the Mann-Whitney test. The new algorithm is based on the U statistic. Exact P-values are reported when both sample sizes are ≤25 and there are no ties.
  • In Correlation tables added an option to hide the upper-right triangular part.

New in MedCalc 20.121 (Nov 29, 2022)

  • Frequencies bar chart: provided options:
  • to enter the counts
  • to sort the bars by magnitude
  • for horizontal display
  • Mann-Whitney test: use the large sample statistic when either size is larger than 15 (previously 20).

New in MedCalc 20.118 (Nov 14, 2022)

  • Improved integration with Windows 11.

New in MedCalc 20.116 (Oct 23, 2022)

  • Import of Excel *.xls files: changed the handling of text cells (removed the leading apostrophe that was added in previous MedCalc versions).

New in MedCalc 20.115 (Sep 9, 2022)

  • Fixed a bug in Passing-Bablok regression that caused the scatter diagram not to show the regression line when Bootstrapping was enabled.
  • Fixed a bug that could cause errors in the post-hoc test of the Friedman test.

New in MedCalc 20.114 (Aug 14, 2022)

  • Fixed a bug in Passing-Bablok regression that caused the scatter diagram not to show the regression line when Bootstrapping was enabled.

New in MedCalc 20.113 (Jul 20, 2022)

  • Fixed a bug in Outlier detection when the Shapiro-Francia normality test was used. In that case the linked values did not always redirect to the correct cases in the spreadsheet.

New in MedCalc 20.112 (Jul 8, 2022)

  • Fixed a bug that could cause, in some cases, the use of wrong markers for subgroups in scatter diagrams.

New in MedCalc 20.110 (May 22, 2022)

  • Fixed a bug in the display of the selected significance level for the post-hoc tests in Anova and Kruskall-Wallis test.

New in MedCalc 20.109 (May 8, 2022)

  • Fixed a bug in the normality test for residuals in several tests (the results of the Kolmogorov-Smirnov test were not displayed).
  • Several other bug fixes and improvements.

New in MedCalc 20.104 (Mar 30, 2022)

  • Corrected a problem in the calculation of Nagelkerke's R2 in Logistic and Probit regression, in case of a large null model −2 Log Likelihood.
  • Corrected a problem that caused failure of saving very large Excel files (*.xlsx).
  • When bootstrapping takes a long time, a dialog box is displayed with the estimated time left, and a button to interrupt the procedure.
  • New: scientific, mathematical and system Constants.
  • New functions: Random, Pow10, CountIf, SumIf, BOXCOX Box-Cox transformation, and BOXCOXINV inverse of the Box-Cox transformation.
  • Improved speed of several statistical procedures.

New in MedCalc 20.100 (Mar 24, 2022)

  • Corrected a problem in the calculation of Nagelkerke's R2 in Logistic and Probit regression, in case of a large null model −2 Log Likelihood.
  • Corrected a problem that caused failure of saving very large Excel files (*.xlsx).
  • When bootstrapping takes a long time, a dialog box is displayed with the estimated time left, and a button to interrupt the procedure.
  • New: scientific, mathematical and system Constants.
  • New functions: Random, Pow10, CountIf, SumIf, BOXCOX Box-Cox transformation, and BOXCOXINV inverse of the Box-Cox transformation.
  • Improved speed of several statistical procedures.

New in MedCalc 20.027 (Jan 25, 2022)

  • Fixed a problem that caused the program to block when ROC curve analyis was used in very large sample.

New in MedCalc 20.026 (Jan 13, 2022)

  • Fixed a bug that caused the Wilcoxon Signed Rank test not to calculate a small sample size test statistic in some circumstances.

New in MedCalc 20.023 (Dec 26, 2021)

  • Fixed a bug in the Undo function of the spreadsheet.
  • Reversed the order of the arguments in the spreadsheet functions CELL and CELLVALUE.

New in MedCalc 20.022 (Dec 16, 2021)

  • Added an option to create a backup copy (*.mc1.bak.zip) when you save a *.mc1 file. See Save options.
  • Some user-interface and performance improvements.

New in MedCalc 20.018 (Dec 1, 2021)

  • In Reports added a button to extract an analysis or graph into a separate window.
  • Added an option to increase the number of decimal places used in reports, see Reports options.
  • The dialog boxes for the calculators in the Tests menu and Sample size menu are now non-modal. This means that you can have several calculators open at the same time, without preventing access to the rest of the program.
  • Improved algorithm for identifying data points in graphs.

New in MedCalc 20.015 (Oct 31, 2021)

  • Added an option to slightly shift ("jitter") coincident data points in scatter diagrams so that the markers do not completely overlap. See Applying jitter in scatter diagrams.
  • Several other minor improvements.

New in MedCalc 20.014 (Oct 11, 2021)

  • Several minor bug fixes and improvements.

New in MedCalc 20.013 (Sep 21, 2021)

  • Fixed a bug in Logistic regression which caused the regression curve not to be displayed in the graph.

New in MedCalc 20.010 (Aug 20, 2021)

  • Modified report for Cox proportional-hazards regression includes Harrell's C-index with 95% confidence interval.
  • Revised layout of Copy graph options and Export graph options
  • In Copy graph options, provided an option Also copy in SVG format. Copying graphs in SVG format is recommended when you are using Office 2016 (when all Office updates are installed), Office 2019 or Office 365.
  • Added the confidence interval of the difference in Comparison of correlation coefficients.
  • Fixed a bug in the calulation of the specificity corresponding to the Youden index in ROC curve analysis.
  • Fixed a problem in formatting the legend in Bland-Altman plots.

New in MedCalc 20.0.8 (Jun 10, 2021)

  • Several bug fixes and minor imporvements.

New in MedCalc 20.0.7 (Jun 9, 2021)

  • Several bug fixes and minor imporvements.

New in MedCalc 20.0.6 (Jun 3, 2021)

  • The Bland-Altman plot and Bland-Altman plot with multiple measurements per subject procedures now also generate a report in addition to the graph.

New in MedCalc 20.0.5 (Jun 1, 2021)

  • Added Partial area under ROC curve and Comparison of partial areas under ROC curves
  • In Comparison of Precision-Recall curves added a choice between paires samples or independent samples design.

New in MedCalc 20.0 (May 13, 2021)

  • Added Sample size calculation for Area Under the Precision-Recall curve.
  • Changed the method of calculating the confidence interval for the AUC of precison-recall curves to the Logit method of Boyd et al (2013). The bootstrap method remains available for calculating the confidence interval for the difference of AUCs of two precison-recall curves.
  • Added a Subgroups option in Comparison of multiple methods.
  • Possibility to enter user-defined values that indicate missing values (e.g. NaN, -99999). This can be found in File menu ➔ Properties ➔ Missing values tab.
  • Color option for missing values (Options panel).
  • New spreadsheet functions USRMISSING() and ISMISSING().
  • Moved option Enter key moves cell pointer to the Edit menu.
  • Expanded color palette for graphs; includes selected colorblind safe colors (Wong, 2011).
  • New color selectors.
  • Added icons for common menu items.

New in MedCalc 19.8 (Mar 29, 2021)

  • Added the (exact mid-P double sided) P-value for incidence rate ratio.
  • Fixed a problem with the display of numbers (in some cases) when using a digit grouping symbol.
  • Provided an option to make all the markers the same across all individuals in Bland-Altman plot with multiple measurements per subject.

New in MedCalc 19.7 (Feb 25, 2021)

  • Added Violin plots

New in MedCalc 19.6.4 (Jan 19, 2021)

  • Several bug fixes, minor changes, and improvements.

New in MedCalc 19.6.3 (Jan 16, 2021)

  • Several minor changes, bug fixes and improvements.

New in MedCalc 19.5.3 (Oct 1, 2020)

  • Added Egger's and Begg's tests for publication bias in meta-analysis
  • Some bug fixes

New in MedCalc 19.5 (Sep 3, 2020)

  • Added:
  • Precision-recall curve
  • Comparison of precision-recall curves
  • Added support for SVG files (an image file format):
  • SVG stands for Scalable Vector Graphics
  • SVG images can be edited with Adobe Illustrator, CorelDRAW, Inkscape (Free!), and other popular vector drawing programs (and even with a text editor)
  • SVG images are scalable
  • SVG images can be printed with high quality at any resolution
  • SVG graphics do NOT lose any quality if they are zoomed or resized

New in MedCalc 19.4.0 (Jul 1, 2020)

  • Added Cochran–Mantel–Haenszel test.
  • Added the C-statistic (which is the area under the ROC curve) in Cox proportional-hazards regression.
  • Added an option to create a Heat map in scatter diagrams.
  • Minor change in the drawing of CI bars in Kaplan-Meier survival curves.
  • Corrected a problem in the evaluation of the OR() function.
  • Corrected a problem in copying/pasting results from dialog panels.

New in MedCalc 19.3 (May 24, 2020)

  • New reports feature allows to compile several analyses into one single report.
  • Completely revised Help (F1) function: when your computer is connected to the internet (and can reach https://www.medcalc.org) the help function shows the same complete documentation as the manual on the website.
  • Support for Windows XP has been dropped.

New in MedCalc 19.2.5 (May 10, 2020)

  • Several bug fixes.
  • New spreadsheet function AGGREGATE

New in MedCalc 19.2.3 (May 1, 2020)

  • Several bug fixes.

New in MedCalc 19.1.6 (Jan 25, 2020)

  • Added a "Complementary cumulative frequency" option for Cumulative frequency distribution plot.

New in MedCalc 19.1.5 (Jan 9, 2020)

  • Added a measure of accuracy in the results for Diagnostic test.
  • Fixed a problem with the display of text in graphs that occurred in some Windows 10 editions.
  • Some minor bug fixes.

New in MedCalc 19.1.3 (Nov 21, 2019)

  • Added a measure of accuracy in the results for Diagnostic test.
  • Fixed a problem with the display of text in graphs that occurred in some Windows 10 editions.
  • Some minor bug fixes.

New in MedCalc 19.1 (Sep 12, 2019)

  • When ROC curve analysis uses bootstrapping (e.g. to calculate the CI of the Youden index), the bootstrap CI of the AUC is also reported.
  • Improved procedure for calculating the Hodges-Lehmann median difference, allowing for larger sample sizes.
  • Improved execution time of Fisher exact test.

New in MedCalc 19.0.5 (Jun 17, 2019)

  • Cumulative frequency distribution: fixed a problem in defining the X-axis when the option 'Display Normal distribution" is selected.
  • Probit regression: fixed a problem that caused the program to generate a message "Could not solve equation" in some datasets.
  • Some minor improvements and bug fixes

New in MedCalc 19.0.3 (May 7, 2019)

  • Corrected a problem when printing a graph that caused the graph not to be positioned correctly on the paper.
  • Corrected a problem in the display of negative numbers in reports that sometimes caused a layout problem (most notably in the display of the regression equation of Passing-Bablok regression).
  • Some other minor bug fixes.

New in MedCalc 18.11.6 (Mar 2, 2019)

  • Responsiveness: added an option to calculate differences as 1st minus 2nd measurement (default is 2nd minus 1st).
  • Added a table with slope and intercept of the different sections of an isotonic regression curve in the Info panel of the scatter diagram.
  • New spreadsheet functions Fisher(a,b,c,d), FisherR2Z(r) and FisherZ2R(z)
  • Various bug fixes an dminor improvements.

New in MedCalc 18.11.3 (Jan 3, 2019)

  • Added 90% confidence interval option in the Independent samples t-test or Paired samples t-test to facilitate equivalence testing.

New in MedCalc 18.11.0 (Nov 20, 2018)

  • Added Isotonic regression curve as an option in scatter diagram and multiple line diagram (implemented using the pool adjacent violators algorithm).
  • Fixed a problem that could impede scrolling through a large file.
  • Improved speed of importing xlsx (Excel) files that contain lots of text cells.
  • Fixed a problem in recognizing some variable names when the decimal symbol is not a dot.

New in MedCalc 18.10.2 (Oct 22, 2018)

  • Added the possibility to use a filter in the different selectors for variables. When you have a large list of variables, you can limit the number of variables that is listed in the drop-down list by using ? as a wildcard in the beginning or at the end of a string. For example, when you have variables VAR_01, VAR_02, VAR_03 in a long list of variables, you can filter these by entering VAR? and next click the dropdown button to obtain a filtered list.

New in MedCalc 18.10 (Oct 4, 2018)

  • Added a list of observed values in the Filter editor dialog box - see Filter formula editor.
  • In all statistical dialog boxes, when the focus is on a variable selector or a filter selector, you can press function key F8 to call the formula editor.
  • Fixed a bug that could cause the program to crash when the option "List variables alphabetically" was not selected.
  • Removed the obsolete "Large dialogs" option.

New in MedCalc 18.9 (Sep 3, 2018)

  • Added Comparison of Independent ROC curves in the Statistics menu (comparion of AUC between subgroups).
  • Fixed a problem in Logistic regression which could cause the program to crash when sample size is small.
  • Fixed an error message that could popup when the program starts.
  • Fixed a bug in saving & recalling Partial correlation.
  • Fixed a bug that caused the Standardized Response Means not to be calculated for some data.
  • Fixed a bug that could cause the program to crash when pasting data in the spreadsheet.

New in MedCalc 18.5 (May 17, 2018)

  • Sample files: when you upgrade the software, the existing sample data files (located in "DocumentsMedCalcSample files") are overwritten by new versions of these files.
  • Added Comparison of (independent) Coefficients of Variation in the Tests menu.
  • In Logistic regression, added an option to plot the logistic regression curve. This is option is only available when there is just one single independent variable.
  • Added semipartial correlation to the results of Multiple regression.
  • Kruskal-Wallis test: added Dunn's test as an optional post-hoc test.
  • Multiple variables graphs: fixed a problem with line colors and styles in Dot & line diagram with large number of cases.
  • Fixed a problem in Forest plots causing the markers in the graph to be badly formatted.
  • Fixed a problem in the Summary statistic table which caused the results of the Normality test not to be displayed.
  • Fixed in bug in the DEC2HEX function which could cause the program to crash when the argument was a negative number.

New in MedCalc 18.2.1 (Feb 23, 2018)

  • Added options to reverse the order of categories in Frequencies bar charts
  • New options for Passing-Bablok regression:
  • Bootstrapping of the CI of the regression parameters.
  • Estimation of bias at selected threshold values, according to CLSI guideline EP09-A3 (2013).
  • Fixed a problem in Age-related reference intervals (related to Box-Cox transformation) that would cause confidence intervals to be displayed incorrectly.
  • Fixed a bug that disabled formatting of trendlines in some cases.
  • Corrected a problem that caused Cox & Snell R2 and Nagelkerke R2 not to be calculated in some instances.

New in MedCalc 18.0.0 (Jan 5, 2018)

  • In Bland & Altman plot, added an option to plot the values against the sample rank, to produce a "Ranked order difference plot" according to CLSI, 2013.
  • In residuals plots for Deming and Passing & Bablok regression, values outside the 4 SD range are plotted in a warning color.
  • Made the calculation of Spearman's rank correlation coefficient in Passing & Bablok regression regression optional.
  • Added an option to insert header/separator bars with file name and current date and time in the Word document, when using the Save to or append to Word file procedure.
  • Fixed some issues in Case-Control matching. Added an option "Exact match" that allows to match non-numerical data (for example, a variable Gender that is coded "Male" and "Female").
  • Fixed some problems with the display of the legends in Deming and Passing & Bablok regression regression plots.
  • Fixed a bug in recalling multiple line graphs with trendlines (trendlines did not appear).

New in MedCalc 17.9.6 (Oct 23, 2017)

  • Several bug fixes and minor revisions

New in MedCalc 17.9 (Oct 2, 2017)

  • In Bland-Altman plots, replaced horizontal lines for confidence intervals with error bars.
  • Revised calculations for Bland-Altman plot with multiple measurements per subject, according to Zou GY (2013) Confidence interval estimation for the Bland-Altman limits of agreement with multiple observations per individual. Statistics in Medicine 22:630-642

New in MedCalc 17.8 (Aug 18, 2017)

  • Added chi-square test in Multiple frequency tables.
  • Support for Complex numbers in the MedCalc spreadsheet.
  • Many minor changes, bug fixes and improvements.

New in MedCalc 17.7.2 (Jul 28, 2017)

  • Added the Hodges-Lehmann location estimator in the results section of the Signed rank test, and the Hodges-Lehmann median difference in the results section of the Mann-Whitney test and Wilcoxon test.
  • Added geometric and harmonic mean as options in Summary statistics table.
  • Added spreadsheet functions HARMEAN and VHARMEAN
  • Added harmonic and geometric mean (without the need for logarithmic transformation) as options in Summary statistics.
  • Several bug fixes.

New in MedCalc 17.7 (Jul 27, 2017)

  • Added the Hodges-Lehmann location estimator in the results section of the Signed rank test, and the Hodges-Lehmann median difference in the results section of the Mann-Whitney test and Wilcoxon test.
  • Added geometric and harmonic mean as options in Summary statistics table.
  • Added spreadsheet functions HARMEAN and VHARMEAN
  • Added harmonic and geometric mean (without the need for logarithmic transformation) as options in Summary statistics.
  • Several bug fixes.

New in MedCalc 15.11.4 (Nov 28, 2015)

  • Improved formatting of Box-and-whisker plots in Clustered Multiple Comparison graphs and Clustered Multiple Variables graphs.
  • Improved auto-update.

New in MedCalc 15.11.3 (Nov 23, 2015)

  • Fixed a bug in Repeated measures ANOVA that caused an error in the calculation of the Sum of Squares for the Factor in Test of Within-Subjects Effects. The error could (only) occur in two-factor studies with repeated measures on one factor with unbalanced design.
  • Improved auto-update.

New in MedCalc 15.11 (Nov 6, 2015)

  • Chi-squared test: the use of Yates' correction for continuity is no longer recommended. For a 2x2 table, MedCalc version 15.11 uses the "N-1" Chi-squared test as recommended by Campbell (2007) and Richardson (2011). This is also applicable in Comparison of proportions.
  • For the McNemar test (comparison of paired proportions) P-values are now always based on the cumulative binomial distribution.
  • Fixed a bug that could cause an error in the calculation of the mean survival time in Kaplan-Meier survival analysis.

New in MedCalc 15.10 (Oct 23, 2015)

  • Added Probit regression (Dose-Response analysis).
  • Improved stable algorithm for sorting spreadsheet data.
  • Chi-squared test: when the degrees of freedom is equal to 1 (in case of a 2x2 table) MedCalc now gives both Chi-squared and Yates' corrected Chi-squared. The use of Yates' correction for continuity is recommended.
  • Some minor Windows 10 compatibility fixes.

New in MedCalc 15.8 (Aug 14, 2015)

  • Added a Funnel plot in meta-analysis.
  • Added a Generic inverse variance method for meta-analysis.
  • Improved Draw ellipse tool: press the shift key to draw a circle.
  • Fixed a bug that could prevent to copy data from an Excel (xlsx) file created with MedCalc.
  • Some minor Windows 10 compatibility fixes.
  • Some speed improvements.

New in MedCalc 15.6 (Jun 2, 2015)

  • New Format graph options:
  • Side margins: this option lets you set a margin between the chart's boundary and lines for the X and Y axis.
  • Allow exponential notation: when this option is selected, the program will display small or high numbers in exponential notation.
  • New option in Kruskal-Wallis test:
  • Jonckheere-Terpstra trend test.
  • New spreadsheet functions:
  • ANY(test,value[,value,...]) returns 1 or TRUE if the value of test matches any of the subsequent values; returns 0 or FALSE otherwise
  • PROPER(str) sets the first character in each word to uppercase and the rest to lowercase
  • E() returns Euler's constant 2.718281828459...
  • BinomialLow(successes,trials,ival) returns the lower bound of the ival% Confidence Interval of the Binomial probability of a number of successes in a number of trials
  • BinomialHigh(successes,trials,ival) returns the upper bound of the ival% Confidence Interval of the Binomial probability of a number of successes in a number of trials
  • Revised spreadsheet functions:
  • ROW(cell) returns the row number of a spreadsheet cell
  • COLUMN(cell) returns the column number of a spreadsheet cell

New in MedCalc 15.5 (May 27, 2015)

  • Additions in Logistic regression: Wald statistic, Cox & Snell R2 and Nagelkerke R2.
  • Fixed a bug that prevented to paste formulas (values were pasted).
  • Several other minor bug fixes, changes and improvements.

New in MedCalc 15.4 (Apr 29, 2015)

  • Added a Correlogram as an option in Correlation table.
  • Significant results with P

New in MedCalc 15.2.1 (Feb 24, 2015)

  • Added descriptive statistics (median, range, quartiles) in the results for the Kruskal-Wallis test.
  • Added drawing of error bars, see Add graphical objects.
  • Added the possibility to place the user-drawn graphical objects (text boxes, frames, connectors, etc.) in the background (right-click the object and select "Send to back" repeatedly).
  • Fixed a bug that caused saved reports that used status data (like in ROC curve analysis) not to be saved correctly.

New in MedCalc 15.1 (Feb 12, 2015)

  • Some revisions in the user-interface.
  • New multilingual interface with choice of different languages for user interface and output:
  • user interface: the language that is used in menus, dialogs, and other user interface elements.
  • output: the language that is used in reports and graphs.
  • The available languages are: English, Chinese (simplified and traditional), French, German, Italian, Japanese, Korean, Polish, Portuguese (Brazilian), Russian and Spanish. To select a different language you go to Tools menu ⇾ Options where you can select your language in the Language section.
  • The help file and software documentation are available in English only.

New in MedCalc 14.12 (Dec 5, 2014)

  • Added options to save the contents of the dialog boxes in the Tests and Sampling menu as text files. In these dialog boxes you can: press function key F9; or right-click in the dialog box title bar and select the corresponding item in the context menu.
  • Reorganized help file.
  • Several minor bug fixes.

New in MedCalc 14.10.2 (Oct 17, 2014)

  • Fixed a problem that could cause the program to crash when closing a statistical report.

New in MedCalc 14.8.1 (Sep 1, 2014)

  • Added comparison of regression lines in results section of Regression.
  • Added Homogeneity of regression slopes in results section of Analysis of covariance.
  • Added the AUC (Area under the ROC curve) in the results of Diagnostic test (2x2 table).
  • Corrected a problem in the calculatation of BCa bootstrap confidence intervals in ROC curve analysis.
  • Changed the method for calculation of Kendall's Tau correlation coeffcient from percentile bootstrap to BCa bootstrap confidence intervals.
  • Changed the random number generator used in bootstrapping to the Mersenne twister (implementation MT19937) (Matsumoto & Nishimura, 1998).
  • Some other minor improvements and bug fixes
  • New version numbers:
  • Starting August 2014, the MedCalc version number has been revised. The new version number consists of a year and month number, and a third number which is a minor revision number.

New in MedCalc 13.3.1 (Jul 12, 2014)

  • In Histograms, when all observations equal class boundaries, the bars are drawn above the class values.
  • Added a subgroups option in Cumulative frequency distribution graphs.
  • Added user-control for Bootstrapping options (number of iterations, random-number seed). Bootstrapping is used for the calculation of Confidence Intervals for Kendall's tau (Rank correlation), reference intervals calculated using the robust method, and some statistics in ROC curve analysis.
  • Some other minor imporvements

New in MedCalc 13.3 (Jun 21, 2014)

  • Added Age-related reference interval calculation
  • Added Weighted regression (in Regression, Scatter diagram with regression line and Multiple regression).
  • Fixed a bug in the calculation of the P-value for Shapiro-Wilk and Shapiro-Francia normal distribution tests.
  • Many other minor changes and improvements.

New in MedCalc 13.2.2 (May 22, 2014)

  • Added the Variance Inflation Factor (VIF) in the results of multiple regression.
  • Fixed a bug in Clustered Multiple Variables graphs with logarithmic transformation.
  • Fixed various minor bugs.

New in MedCalc 13.2 (May 7, 2014)

  • Modified the options for disease prevalence in the ROC curve analysis dialog box.
  • Added an option in the results of the Chi-squared test to display all counts as percentages of row, column and global totals.
  • Added an input box for Digit grouping symbol in the MedCalc options.
  • Added an option to use the digit grouping symbol for formatting numbers in graphs (see Graph schemes).
  • Modified drawing of graphs when the option Outside tick marks is selected.
  • Added standard deviation of groups in the output for ANOVA.
  • Added an option in the context menu of scatter diagrams to draw a user-defined function. The context menu appears when you right-click in the scatter diagram.
  • Fixed a bug that would sometimes cause the program to crash in Reference interval calculation
  • Several other minor bug fixes

New in MedCalc 13.1.2 (Apr 11, 2014)

  • Added the z (or t) statistic and P-values for the pooled effect sizes in meta-analysis.
  • Several compatibility fixes.

New in MedCalc 13.1.0 (Mar 17, 2014)

  • Renamed the Categorical data submenu into Crosstabs.
  • New: Relative risk & Odds Ratio in the Statistics menu (calculated on a 2x2 table compiled from data in the spreadsheet).
  • Revised dialog boxes and presentation of results for Relative risk and Odds ratio in the Tests menu.
  • Some bug fixes.

New in MedCalc 13.0.2.0 (Feb 19, 2014)

  • Fixed a bug that caused context menu items to remain disabled after printing a graph or report

New in MedCalc 13.0.1.0 (Feb 19, 2014)

  • Fixed a bug in the SNK and Tukey-Kramer post hoc test in ANOVA that would result in false-positive results in some cases
  • Some minor bug fixes and user interface improvements

New in MedCalc 13.0.0.0 (Feb 1, 2014)

  • New: Nonlinear regression.
  • Added trend line options in scatter diagrams: moving average trend line, LOESS smoothed trend line or reduced major axis line.
  • Added LOESS smoothed trend line in Multiple lines graph.
  • When a Moving average or LOESS smoothed trend line is included in a graph, the graph windows has a status bar that includes a trackbar with which you can control the degree of smoothing.
  • New: Polar plot.
  • New: Function plot.
  • Added an input box for Disease prevalence in Diagnostic test evaluation.
  • New spreadsheet functions:
  • new mathematical functions: ACOSH, ASINH, ATANH, ATAN2
  • new statistical functions: CORREL, SLOPE
  • new statistical functions on variables: VCORREL, VSLOPE
  • new engineering functions: BesselI, BesselJ, BesselK, BesselY, ERF, ERFC, Dec2Hex, Hex2Dec
  • "Selection criterion" has been renamed to "Filter".
  • Large dialogs option: option to make all dialog boxes larger and easier to read

New in MedCalc 12.7.7 (Jan 8, 2014)

  • Fixed various bugs

New in MedCalc 12.7.5 (Oct 10, 2013)

  • Fixed a bug causing subgroups in scatter diagrams not always to be presented correctly.

New in MedCalc 12.7.4 (Sep 28, 2013)

  • Modified the DAYNAME() and MONTHNAME() functions to take an additional language parameter.
  • Different sorting procedures take into account names of days and months so these are ordered sequentially, not alphabetically.
  • New REVERSE() string function.
  • Added an option to show the line of equality (y=x line) in the scatter diagram (Regression submenu).
  • Fixed a bug that would cause the program to hang when importing xlsx files that contained very long text values.
  • Updated the algorithm for the log-rank test in survival analysis in case the number of subjects at risk drops to 1.
  • The selection of a unit for angle (radians, degrees, grades) has been removed from the Options panel. Parameters of all trigonometric functions must now be in radians. To convert from degrees to radians use the new RADIANS function and to convert from radians to degrees use the new DEGREES function.
  • New trigonometric spreadsheet functions:
  • COSH(x) Hyperbolic cosine function
  • SINH(x) Hyperbolic sine function
  • TANH(x) Hyperbolic tangent function
  • New statistical spreadsheet functions:
  • GAMMA(r) Gamma function
  • GAMMALN(r) Logarithm of the Gamma function

New in MedCalc 12.7.2 (Aug 26, 2013)

  • Added the Shapiro-Wilk and Shapiro-Francia tests for Normality, available in Summary statistics, Outlier detection and Reference interval procedures.
  • Q-Q plot option, see Normal plot.
  • Improved algorithm for deciding to use logarithmic transformation and non-parametric test selection in the Serial measurements analysis when the option Automatic statistical analysis is selected.
  • Fixed a bug that caused the program to use alphabetical ordered subgroups in Clustered multiple comparison graphs and Clustered multiple variables graph, and not the user defined order.
  • Fixed a bug that caused the program to hang when calculating a reference interval using the robust method in some datasets.
  • Other minor bug fixes.

New in MedCalc 12.7.0 (Jun 17, 2013)

  • Added meta-analysis of Area under ROC curve
  • Added mean survival time with 95 % CI and the 95% CI for the median survival time in Kaplan-Meier survival analysis.
  • Changes in Cox regression:
  • Added option to plot 100-Survival probability.
  • Added the Wald statistic in the output.
  • Several other changes and additions in the output of the Kaplan Meier and Cox regression procedures.
  • Added Regression through the origin.
  • Some bug fixes.

New in MedCalc 12.6.1 (May 22, 2013)

  • Choice of different post-hoc tests in one-way ANOVA: Student-Newman-Keuls, Tukey-Kramer or Scheffé test.
  • Choice of significance level for the post-hoc tests in one-way ANOVA, Kruskal-Wallis test, Friedman test, and Cochran's Q.

New in MedCalc 12.6.0 (May 21, 2013)

  • Improved meta-analysis with new procedures for:
  • Correlation
  • Proportion
  • Relative risk
  • Risk difference
  • Alpha and Beta values for sample size calculations can now take any user-defined value.
  • Sampling for a single mean has been reprogrammed according to Machin D, Campbell MJ, Tan SB, Tan SH (2009) Sample size tables for clinical studies. 3rd ed. Chichester: Wiley-Blackwell. Before, it was programmed according to Kirkwood BR, Sterne JAC (2003) Essential medical statistics, 2nd ed. Oxford: Blackwell Scientific.
  • Fixed a bug in the calculation of Cox proportional-hazards regression with nominal categorical variables.

New in MedCalc 12.4.1.0 (Mar 29, 2013)

  • Resizable dialog boxes.
  • New summary measure in Serial measurements: % of time below or above a certain value.
  • Revised ROC curves sample size calculations allow for unequal sample sizes in the positive and negative groups.
  • New spreadsheet functions LOGIT and ALOGIT

New in MedCalc 12.4.0.0 (Jan 3, 2013)

  • Added Forest plot as a separate graphing option (not linked to meta-analysis).
  • Added an AutoRecover option, see Options.
  • Many minor improvements and bug fixes.

New in MedCalc 12.3.0.0 (Jul 10, 2012)

  • Expanded ROC curve analysis with:
  • calculation of a confidence interval for the Youden index and associated criterion value
  • estimation of sensitivity and specificity at fixed specificity and sensitivity
  • calculate optimal criterion value taking into account costs of various decisions.
  • Added Partial correlation: correlation adjusted or corrected for the influence by other variables.
  • Added calculation of required sample size for comparison of two survival rates (logrank test). See Survival analysis (logrank test).
  • Fixed a bug that could cause the 64-bits version of the program to hang in Repeated Measures Anova.
  • Fixed a bug that could cause datafile reading errors when it contains statistical tables with more than 60 variables.
  • Fixed a bug that could cause the program to hang in the Bland-Altman plot with multiple measurements per subject.
  • Fixed a bug in the calulation of the IF(condition,argtrue,argfalse) function. When condition is true, errors in the calculation of argfalse will no longer cause the IF function to fail.

New in MedCalc 12.2.1.0 (Jul 10, 2012)

  • Reprogrammed the P-value for Kurtosis according to Sheskin 2011 (previously it was programmed according to Sheskin 2004). This results in a different P-value when Kurtosis is negative, and in this case also influences the result of the D'Agostino-Pearson test for Normality:
  • Sheskin DJ (2004) Handbook of parametric and nonparametric statistical procedures. 3rd ed. Boca Raton: Chapman & Hall /CRC.
  • Sheskin DJ (2011) Handbook of parametric and nonparametric statistical procedures. 5th ed. Boca Raton: Chapman & Hall /CRC.

New in MedCalc 12.2.0.0 (Jul 10, 2012)

  • Added a context menu item for the Multiple ROC plot to mark the point corresponding with the highest Youden index.
  • Fixed a bug that could cause datafile reading errors when it contains statistical tables with more than 60 variables.
  • Fixed a bug that could cause the program to hang in the Bland-Altman plot with multiple measurements per subject.
  • Fixed a bug in the calculation of the IF(condition,argtrue,argfalse) function. When condition is true, errors in the calculation of argfalse will no longer cause the IF function to fail.

New in MedCalc 12.1.4.0 (Jul 10, 2012)

  • Fixed a problem in the Histogram graph were bars representing less than a small percentage of cases (less than 0.1%) of total cases were not always visible.

New in MedCalc 12.1.1 (Nov 23, 2011)

  • Fixed a bug in Kaplan Meier survival analysis where the Chi-square test for trend was not always executed.
  • Fixed a bug in saving and restoring Summary statistics and Correlation tables.

New in MedCalc 12.1 (Nov 23, 2011)

  • Added an option to draw the Line of equality in a Scatter diagram.
  • Some bug fixes.

New in MedCalc 12 (Nov 23, 2011)

  • This update is available in different versions for 32-bits and 64-bits Windows editions. The 32-bits version will work both Windows editions. The 64-bits version will work on 64-bits Windows editions only
  • If you want to install the 64-bits version and you have an older MedCalc version already installed, you should first remove that older MedCalc version through your Windows control panel
  • How to determine whether a computer is running a 32-bit version or 64-bit version of the Windows operating system (link to Microsoft website)
  • MedCalc 12 does not work on Windows 2000 or prior versions of Windows. Windows 2000 reached the end of its lifecycle on 13 July 2010. It does no longer receive new security updates and new security-related hotfixes. Therefore it is strongly advised to switch to a newer version of Windows
  • File compatibility: this new MedCalc version can open and read MedCalc files created by any older version of the software. Files created with this new version (new files or saved files) cannot be read by older versions of the software
  • Improved support for Asian languages
  • List variables alphabetically (see Options): when this option is selected, variables are listed alphabetically in the selector boxes for variables. When this option is not selected, the variables are listed in the order they are entered in the spreadsheet. This option does not influence the order of the variables in the spreadsheet
  • Auto-complete function in selectors for variables and selection criteria (see Options)
  • When you select a variable or selection criterion you can press function key F8 to call the formula editor for variables or selection criteria
  • Added the posibility to assign labels to data values. These labels are used for subgroup identification in graphs
  • Columns can be formatted specifically to contain date and time data. See Format spreadsheet (Column tab), How to enter dates
  • Changes in Passing & Bablok regression
  • Exact P-value for the cusum linearity test
  • Added option to calculate perpendicular residuals (see Passing & Bablok, 1983)
  • Added an option to plot the residuals by rank order (see Passing & Bablok, 1983)
  • Added Number Needed to Treat (NTT) with its 95% CI to the results of Relative risk
  • Added option to save prognostic indices in Cox proportional hazard regression
  • Added the Hosmer & Lemeshow test in Logistic regression
  • Added an option to plot a moving average in Multiple line graph
  • Save graph as a PowerPoint slide (see Export graphs)
  • New ISEMPTY() function. See Logical functions
  • Change of the method for the calculation of the Standard Error (SE) of the Area Under the ROC Curve according to Hanley & McNeil (1982). Hanley & McNeil give 2 methods for the calculation of the SE, one in table II (p. 31) and one using equation 2 on page 33. The latter was used in previous versions of MedCalc
  • Added the calculation of exact binomial confidence intervals for positive and negative predictive value in the Predictive values calculator, if sample size is known

New in MedCalc 11.6.2 (Nov 23, 2011)

  • Fixed a bug in the cusum linearity check in Passing & Bablok regression and report an exact P-value instead of "P0.05".

New in MedCalc 11.6.1 (Nov 23, 2011)

  • Fixed a bug in the use of decimal symbol and list separator (regional settings).

New in MedCalc 11.6 (Nov 23, 2011)

  • New: Outlier detection: offers several methods of outlier detection.
  • New: Responsiveness: offers several indexes of ability to detect change.
  • New: Stack columns: stacks several spreadsheet columns into a new column.
  • New: Bland-Altman plot with multiple measurements per subject.
  • New: Coefficient of variation from duplicate measurements.
  • Improved dialog boxes in Tests menu: added the possibility to enter an optional comment and print a report.
  • Improved dialog boxes for Sample size calculaton: added tables that show the required sample sizes for different Type I and Type II Error levels, and the possibility to print a report.
  • Many minor bug fixes.

New in MedCalc 11.5.1 (Feb 21, 2011)

  • Added the possibility to change the width of error bars and middle lines in various graphs.
  • Fixed a bug in the labelling of the X-axis of Multiple line graphs.

New in MedCalc 11.5.0 (Feb 21, 2011)

  • Several bug fixes and performance improvements.
  • Fixed a problem when importing data from large text (CSV) files.
  • Fixed a problem when reading large .xlsx files created by Excel 2007 or 2010.
  • Fixed a problem when reading .xls files created by Excel 2010.

New in MedCalc 11.4.4 (Feb 21, 2011)

  • MedCalc home page was moved from www.medcalc.be to www.medcalc.org
  • Bug fix in the graph for Cox regression where, in some circumstances, the graphs for the different subgroups were mislabelled.

New in MedCalc 11.4.3 (Nov 16, 2010)

  • New: Cronbach's Alpha (internal consistency of a questionnaire).

New in MedCalc 11.4.2 (Nov 16, 2010)

  • Added "Dot plot" as a follow-up command in Intraclass correlation coefficient.

New in MedCalc 11.4 (Oct 2, 2010)

  • New: Cochran's Q test.
  • New: option in the Bland & Altman plot to plot the differences against one of the methods, if this is a reference or "gold standard" method.
  • New: option to copy/paste graphs with landscape or portrait aspect ratio. See Options.
  • New: vertical or horizontal layout option for Summary statistics table.
  • New: Reset graph titles and options command.
  • New: ability to read Stata files (see Open).
  • New: FINV spreadsheet function which returns the inverse of the F probability distribution.

New in MedCalc 11.3.8 (Sep 28, 2010)

  • Fixed a bug in reading and writing xlsx (Excel 2007 & 2010) files.

New in MedCalc 11.3.7 (Sep 28, 2010)

  • Fixed a bug that could result in the need to re-enter the registration data repeatedly.

New in MedCalc 11.3.6 (Sep 28, 2010)

  • Fixed a bug in the Multiple line graph procedure that could cause the program to fail in some circumstances.

New in MedCalc 11.3.5 (Aug 17, 2010)

  • Increased the number of bootstrap replications to establish the confidence intervals for the reference interval estimated using the robust method to 5000.
  • Some minor bug fixes.

New in MedCalc 11.3.3 (Jun 15, 2010)

  • Minor bug fixes (monochrome TIF files and CELL function).
  • Correction of some typographical errors.

New in MedCalc 11.3.2 (Jun 15, 2010)

  • New: option to mark points corresponding to criterion values in ROC graphs.
  • New: option to display small P-values using Engineering Notation.

New in MedCalc 11.3.1 (Jun 15, 2010)

  • Copy/paste graph drawing objects to other graphs.
  • Minor bug fixes

New in MedCalc 11.3.0.0 (May 3, 2010)

  • New: to add lines, frames, ellipses and connectors in graphs: right-click in the graph and select "Add line", "Add rectangle", "Add ellipse" or "Add connector". Next, click in the graph and drag the mouse to create the object. To edit the object's attributes: double-click on the object or right click on the object and select "Format object".
  • New: to add text boxes in graphs: right-click in the graph and select "Add text box". Next click in the graph to place the text box.
  • New: to add reference lines in a graph: right-click in the graph and select "Add horizontal reference line" or "Add vertical reference line", or click in the graph border to pick a new line and drag it to its desired position.
  • Added the possibility to change the properties of different attributes and components in graphs. Right-click on a component and select "Format...".
  • Added multiple Cumulative Frequency Distribution as a graph option in Multiple Variables graphs.
  • Added a multilevel Undo function for changes made to graphs.
  • Option to specify resolution (dpi) when saving graphs as TIF files (default = 96 dpi). Use the Options button in the file selector box to change this value.
  • Removed gradient background in graphs.
  • New Spreadsheet functions AveDev, CoefVar, GeoMean and VAveDev, VCoefVar, VGeoMean.
  • Fixed a bug in the "Print all" option for Youden plots.
  • Reprogrammed Standard Error (SE) for Kappa according to Fleiss et al (2003) and added 95% CI for Weighted Kappa. This results in a slightly different SE than in previous versions. The Standard error for both Kappas is appropriate for testing the hypothesis that the underlying value of kappa is equal to a prespecified value other than zero.
  • Changed calculation of the Hazard ratio in Kaplan Meier survival analysis. The new Hazard ratio is simply the inverse of the ratio calculated with previous versions of the software.

New in MedCalc 11.2.0.0 (Jan 25, 2010)

  • New in Reference Interval estimation: an option to test for outliers, Box-Cox power transformation, a graph option.
  • Added an option for a 2.5-97.5 percentile error bar in different graphs.
  • Changed the formula for the confidence interval of the hazard ratio in Kaplan-Meier survival analysis (Armitage et al., 2002).
  • Fixed a minor bug in the variables list that occurred after editing duplicate column headers.
  • Fixed a bug in Multiple Comparison graphs where labels on the X-axis were converted to uppercase.
  • Changed the formula for the P-value for the Mann-Whitney test (resulting in a different P-value when the number is ties is high).
  • Change in the algorithm for Trimmed mean (the calculated number of cases to trim is now rounded to the closest integer, in previous versions it was truncated).

New in MedCalc 11.1 (Jan 25, 2010)

  • In ROC curve analysis, added the DeLong method (1988) for calculating the Standard Error of the Area Under the Curve (AUC), and of the difference between two AUCs.
  • Added an option to calculate the Confidence Interval for the Area Under the Curve (AUC) as AUC ± 1.96 SE (Standard Error).
  • Added Time-weighted average and Left-align time option in Serial measurements.
  • Added 95% Confidence Interval for Rates and Comparison of two rates.
  • Renamed the "Line" (for means or medians) graph type option into "Connecting Line" and added a new graph type option "Horizontal line" in Data comparison graphs, Multiple comparison graphs, Clustered multiple comparison graphs, Multiple variables graphs and Clustered multiple variables graphs.
  • Redesigned dialog boxes for statistical and graphical procedures with a Data panel on the left and an Options panel on the right side.
  • Data comparison graphs now have editable text on the vertical axis (but no title).
  • Variable name is now the default text on the Y-axis in Multiple comparison graphs and Clustered multiple comparison graphs.
  • Fixed a problem with the marker style for mean or median in the Data comparison graphs.
  • Corrected a bug in the conversion of time data when importing Excel files.
  • Corrected a bug in Multiple Variables graphs where extreme values sometimes were not correctly displayed in box-and-whisker plots.

New in MedCalc 11.0.1 (Jan 25, 2010)

  • Fixed a bug in the Statistical spreadsheet functions on variables (VAVERAGE etc.) that could occur in some instances when sample size is 0.
  • Fixed a bug that caused the Logistic regression procedure to fail in some circumstances.

New in MedCalc 11.0 (Jan 25, 2010)

  • Windows 7 compatibility.
  • Revised icons and toolbars.
  • Faster start-up time.
  • Improved high DPI support (high resolutions screens).
  • Shortened start-up time and increased responsiveness.
  • Merged Format spreadsheet and Format column dialog boxes.
  • Added 95% CI for linear regression coefficients.
  • Many other minor revisions and improvements.

New in MedCalc 10.4 (Jan 25, 2010)

  • Revised reference interval with inclusion of the "robust method" as described in the CLSI Guidelines C28-A3.
  • Added Friedman test.
  • Added Intraclass correlation coefficient.

New in MedCalc 10.1.0.0 (Feb 16, 2009)

  • Added analysis of covariance (ANCOVA). Two-way analysis of variance has been completely revised and the repeated measures of anova has been improved with Greenhouse-Geisser and Huynh-Feldt corrections for non-sphericity.

New in MedCalc 9.3.0.0 (Mar 9, 2007)

  • Certified for Windows Vista.