Gene Construction has an award winning interface design that allows graphic manipulation of DNA sequences in addition to providing sophisticated drawing capabilities for Mac and Windows users.
GCK was named the "Best Plasmid Mapping Software" by the Biotechnology Software and Internet Journal for four straight years.
You can see the construct either as a text sequence or graphically, circular or linear.
Here are some key features of "Gene Construction Kit":
· A powerful productivity tool that no molecular biologist should be without
· Ideal for planning and tracking complex construction projects
· Manipulate actual DNA sequences through a unique and innovative graphical interface
· Automatically monitor and adjust DNA fragment ends during cutting and pasting
· Define thickness, pattern, shape, direction, and color for each DNA segment
· Search, download, and import GenBank and EMBL files with all GenBank feature table items translated automatically into GCK features.
· Unique Chronography feature tracks the history of any given DNA segment and maintains alternative views
· Name and store comments with each generation (view)
· Cut and paste DNA segments from one construct to another (including segment history)
· View predicted electrophoresis patterns of restriction digests including partial digests
· Show DNA with protein sequence and/or with restriction enzyme or other sites of interest
· Create illustrations containing multiple constructs, gels, sequence listings, free text, legends and other graphics
· File Searching module provides sophisticated database-like capabilities
· Create silent mutations to add or remove a restriction site from a sequence without changing the coding information
· Mark restriction sites using one or more completely editable and expandable enzyme lists
· Auto-arrange restirction site markers
· Find Open Reading Frames using any codon table you specify
· Display the name of any region within the construct window
· Frame segments of DNA in the sequence display. Frames can encompass the site markers, sequence, and/or regions of a construct. You can set the frame color and pattern.
· Use 3-letter or 1-letter amino acid representation for protein sequences
· Annotate sequence listings with custom 'adornments' to highlight sequence features
· Display and maniuplate multiple constructs in the same illustration window
· Add arrows, rectangles, ellipses (filled or empty) and text to illustrations
· Select multiple objects in an illustration window and align them vertically and/or horizontally
· Perfect for making color or black and white posters and figures for slides or papers
Limitations:
· can not save
What's New in This Release: [ read full changelog ]
· A new Deluxe Importer Module that contains comprehensive features to allow integrated GenBank and EMBL searching and file retrieval over the Internet with importing directly into Gene Construction Kit.
· A new customizable interface converts all GenBank and EMBL features ‘one-to-one’ to graphical GCK features, enabling molecular biologists to easily work with the latest DNA sequence information available via the Internet.
· Version 2.5 has been carbonized to run natively in Mac OS X allowing users to take full advantage of the new features of this robust operating system, including the powerful graphics engine, Aqua user interface, and improved stability and performance.
· The new version release of Gene Construction Kit is compatible with both Windows and Macintosh platforms. The feature set of GCK version 2.5 on both platforms is the same, and Gene Construction Kit files created on either platform can be read by GCK 2.5 on the opposite platform, simplifying collaborations and data ...
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