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SearchGUI Changelog

What's new in SearchGUI 4.2.17

Sep 28, 2023
  • FEATURE IMPROVEMENT: Updated Sage to version 0.13.3.
  • BUG FIX: Re-added search engine executables that had disappeared in the previous release.

New in SearchGUI 4.2.15 (Jun 19, 2023)

  • FEATURE IMPROVEMENT: Allowed the user to overwrite the location of the Tide index.
  • FEATURE IMPROVEMENT: Made sure the local version of MetaMorpheus is used when setting the folder.

New in SearchGUI 4.2.14 (May 22, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.13.1.

New in SearchGUI 4.2.11 (May 11, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.12.0.
  • LIBRARY UPDATE: Updated utilities to version 5.0.70.

New in SearchGUI 4.2.10 (May 9, 2023)

  • FEATURE IMPROVEMENT: The Tide FASTA index can now be reused (see Tide advanced settings).
  • LIBRARY UPDATE: Updated utilities to version 5.0.69.

New in SearchGUI 4.2.9 (May 9, 2023)

  • FEATURE IMPROVEMENT: Updated Comet to version 2023.01 rev. 2.

New in SearchGUI 4.2.8 (Mar 31, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.10.0.
  • FEATURE IMPROVEMENT: Updated Comet to version 2023.01 rev. 1.
  • LIBRARY UPDATE: Updated utilities to version 5.0.68.

New in SearchGUI 4.2.7 (Mar 9, 2023)

  • BUG FIX: Fixed a bug in the Sage TMT level setting.
  • FEATURE IMPROVEMENT: Updated Sage to version 0.9.4.

New in SearchGUI 4.2.6 (Mar 9, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.9.3.

New in SearchGUI 4.2.5 (Mar 9, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.9.1 adding support for more enzyme types.

New in SearchGUI 4.2.4 (Mar 8, 2023)

  • FEATURE IMPROVEMENT: Updated Sage to version 0.9.0 adding support for more enzyme types.

New in SearchGUI 4.2.2 (Mar 7, 2023)

  • NEW FEATURE: Added support for extracting all spectra (and not just MS2) when parsing mzML files (beta).
  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 1.0.1 (NB: Requires .NET 6.0).
  • FEATURE IMPROVEMENT: Updated Sage to version 0.8.1.
  • FEATURE IMPROVEMENT: Sage is now using the decoy tag from the FASTA parameters (to avoid the use of two different decoy tags).
  • LIBRARY UPDATE: Updated ThermoRawFileParser to version 1.4.2.
  • LIBRARY UPDATE: Updated utilities to version 5.0.65.

New in SearchGUI 4.2.0 (Jan 31, 2023)

  • NEW FEATURE: Added support for Sage (v0.8.0).
  • FEATURE IMPROVEMENT: Updated MS-GF+ to version 2023.01.12.
  • FEATURE IMPROVEMENT: Indexed mzml is now the default for ThermoRawFileParse (as required by Comet).
  • FEATURE IMPROVEMENT: Made sure that the mzml files generated by ThermoRawFileParser uses lower case for the filename extension.
  • BUG FIX: Fixed a bug with using unspecific cleavage in MS-GF+.
  • BUG FIX: Fixed a bug in the multi-enzyme selection dropdown box.
  • LIBRARY UPDATE: Updated utilities to version 5.0.61.

New in SearchGUI 4.1.23 (Oct 26, 2022)

  • BUG FIX: Fixed a bug in the NewEnzymeDialog.
  • LIBRARY UPDATE: Updated utilities to version 5.0.50.

New in SearchGUI 4.1.22 (Oct 24, 2022)

  • LIBRARY UPDATE: Updated utilities to version 5.0.48, supporting Java version numbers with + as separator.

New in SearchGUI 4.1.21 (Oct 3, 2022)

  • LIBRARY UPDATE: Updated utilities to version 5.0.47, updating from http to https in the software setup dialogs

New in SearchGUI 4.1.20 (Sep 27, 2022)

  • BUG FIX: Fixed a bug in the Ensembl mappings.
  • LIBRARY UPDATE: Updated utilities to version 5.0.46, fixing a bug for Java versions without decimals, e.g. just 19.

New in SearchGUI 4.1.19 (Sep 27, 2022)

  • FEATURE IMPROVEMENT: Updated Ensembl to version 104 and Ensembl Genomes to version 51.

New in SearchGUI 4.1.18 (Sep 20, 2022)

  • FEATURE IMPROVEMENT: Updated Comet to an updated version of 2022.01 rev. 2, fixing a spectrum title issue in the pep.xml export.

New in SearchGUI 4.1.17 (Sep 14, 2022)

  • FEATURE IMPROVEMENT: Updated Comet to version 2022.01 rev. 2.

New in SearchGUI 4.1.16 (Sep 13, 2022)

  • FEATURE IMPROVEMENT: Updated Comet to version 2022.01 rev. 1.

New in SearchGUI 4.1.15 (Jul 25, 2022)

  • LIBRARY UPDATE: Updated utilities to version 5.0.44, making sure that already zipped search result files are not zipped twice.

New in SearchGUI 4.1.14 (Jul 25, 2022)

  • LIBRARY UPDATE: Updated utilities to version 5.0.42, fixing a null pointer for TMT-related PTMs.

New in SearchGUI 4.1.13 (Jun 15, 2022)

  • BUG FIX: Updated the link in the check for new versions.

New in SearchGUI 4.1.11 (Jun 8, 2022)

  • FEATURE IMPROVEMENT: Updated Comet to version 2022.01 rev. 0.

New in SearchGUI 4.1.10 (Apr 23, 2022)

  • FEATURE IMPROVEMENT: Added support for Cl, Co, Ni and Mn.
  • LIBRARY UPDATE: Updated utilities to version 5.0.40.

New in SearchGUI 4.1.8 (Feb 21, 2022)

  • BUG FIX: Comet is no longer automatically disabled on Mac in the user interface.
  • BUG FIX: Fixed minor bugs in the secondary progress display.

New in SearchGUI 4.1.7 (Feb 20, 2022)

  • BUG FIX: Fixed a folder error with Tide for Linux.

New in SearchGUI 4.1.6 (Jan 14, 2022)

  • FEATURE IMPROVEMENT: Updated Tide to version 4.1, adding support for PTMs at the protein terminals.
  • LIBRARY UPDATE: Updated utilities to version 5.0.37.

New in SearchGUI 4.1.5 (Jan 9, 2022)

  • FEATURE IMPROVEMENT: Updated MS-GF+ to version 2022.01.07.

New in SearchGUI 4.1.4 (Jan 9, 2022)

  • FEATURE IMPROVEMENT: Updated Comet to version 2021.02 rev. 0 (which adds support for OSX and removes support for Windows 32 bit).
  • LIBRARY UPDATE: Updated utilities to version 5.0.3

New in SearchGUI 4.1.3 (Jan 5, 2022)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.320.
  • LIBRARY UPDATE: Updated utilities to version 5.0.34.

New in SearchGUI 4.1.2 (Nov 15, 2021)

  • FEATURE IMPROVEMENT: Added support for TMTpro 18-plex.
  • LIBRARY UPDATE: Updated utilities to version 5.0.33.

New in SearchGUI 4.1.1 (Nov 8, 2021)

  • FEATURE IMPROVEMENT: Updated MS-GF+ to version 2021.09.06.
  • LIBRARY UPDATE: Updated utilities to version 5.0.29.

New in SearchGUI 4.1.0 (Sep 7, 2021)

  • LIBRARY UPDATE: Updated junit to version 4.13.2.
  • LIBRARY UPDATE: Updated xpp3 to version 1.1.6.
  • LIBRARY UPDATE: Updated utilities to version 5.0.27.

New in SearchGUI 4.0.42 (Aug 11, 2021)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.319, adding the MinAllowedInternalFragmentLength parameter.
  • LIBRARY UPDATE: Updated utilities to version 5.0.25.

New in SearchGUI 4.0.41 (Jul 6, 2021)

  • BUG FIX: Fixed issues with the PTM mappings for Novor and DirecTag when running via the command line.

New in SearchGUI 4.0.40 (Jul 5, 2021)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.318 (note: now requires .NET 5.0.)

New in SearchGUI 4.0.39 (Jun 30, 2021)

  • FEATURE IMPROVEMENT: Updated Comet to version 2021.01 rev. 0.
  • FEATURE IMPROVEMENT: Re-added the OS-dependent MS Amanda versions (now depending on .NET instead of mono).
  • FEATURE IMPROVEMENT: Added support for Java 16.
  • BUG FIX: Made sure that the search and denovo engines are set to executable before running them.
  • LIBRARY UPDATE: Updated utilities to version 5.0.24.

New in SearchGUI 4.0.38 (Jun 29, 2021)

  • BUG FIX: Fixed a gene mapping issue.

New in SearchGUI 4.0.36 (Jun 15, 2021)

  • LIBRARY UPDATE: Updated utilities to version 5.0.22.

New in SearchGUI 4.0.35 (May 25, 2021)

  • FEATURE IMPROVEMENT: Cleaned up the progress display when adding decoys via FastaCLI.
  • LIBRARY UPDATE: Updated utilities to version 5.0.21.

New in SearchGUI 4.0.34 (May 24, 2021)

  • FEATURE IMPROVEMENT: Updated Comet to version 2020.01 rev. 4.

New in SearchGUI 4.0.33 (May 12, 2021)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.317.
  • FEATURE IMPROVEMENT: MetaMorpheus is executed differently when running in a Conda environment (using conda-forge MetaMorpheus package binaries).

New in SearchGUI 4.0.32 (May 11, 2021)

  • FEATURE IMPROVEMENT: Improved the information displayed when indexing spectra.
  • LIBRARY UPDATE: Updated utilities to version 5.0.18, fixing a rare cms-related bug.

New in SearchGUI 4.0.31 (Apr 29, 2021)

  • BUG FIX: Removed a custom settings file that caused the spectrum parsing to fail.

New in SearchGUI 4.0.30 (Apr 29, 2021)

  • BUG FIX: Fixed a backwards compatibility bug for the cms files.
  • LIBRARY UPDATE: Updated utilities to version 5.0.17.

New in SearchGUI 4.0.29 (Apr 26, 2021)

  • BUG FIX: Fixed a bug in X!Tandem in the handling of variable terminal PTMs without specific amino acid targets.
  • LIBRARY UPDATE: Updated utilities to version 5.0.16.

New in SearchGUI 4.0.28 (Apr 23, 2021)

  • FEATURE IMPROVEMENT: Greatly sped up the parsing/indexing of the spectrum files.
  • FEATURE IMPROVEMENT: Removed the Java 1.9 requirement, i.e. only Java 1.8 is now required.
  • FEATURE IMPROVEMENT: Made sure that also the error messages are sent to the standard output when not using the log.
  • LIBRARY UPDATE: Updated ThermoRawFileParser to version 1.3.4.
  • LIBRARY UPDATE: Updated utilities to version 5.0.15.

New in SearchGUI 4.0.27 (Apr 21, 2021)

  • NEW FEATURE: Added a new command line option (use_log_folder) that makes it possible to override the log folder and send the log details directly to the standard output.

New in SearchGUI 4.0.25 (Mar 31, 2021)

  • FBUG FIX: Fixed a bug in the check for duplicate accession numbers in FASTA files.
  • LIBRARY UPDATE: Updated utilities to version 5.0.14.

New in SearchGUI 4.0.24 (Mar 31, 2021)

  • FEATURE IMPROVEMENT: Re-added the check for duplicate accession numbers in FASTA files.
  • LIBRARY UPDATE: Updated utilities to version 5.0.13.

New in SearchGUI 4.0.22 (Mar 11, 2021)

  • BUG FIX:
  • Fixed a bug with the fragmentation setting for MS-GF+ when using the command line.
  • LIBRARY UPDATE:
  • Updated utilities to version 5.0.10.

New in SearchGUI 4.0.21 (Mar 11, 2021)

  • BUG FIX:
  • Fixed a bug with the use of custom enzymes in MS-GF+

New in SearchGUI 4.0.20 (Mar 9, 2021)

  • FEATURE IMPROVEMENT: Made the FASTA header parsing (slightly) more robust.
  • LIBRARY UPDATE: Updated utilities to version 5.0.9.

New in SearchGUI 4.0.19 (Mar 9, 2021)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.315.
  • BUG FIX: Fixed a bug in the saving of min/max peptide lengths for Comet.
  • LIBRARY UPDATE: Updated utilities to version 5.0.8.

New in SearchGUI 4.0.18 (Feb 24, 2021)

  • FEATURE IMPROVEMENT:
  • The Java version warning now appears if using Java 8 or older.
  • LIBRARY UPDATE:
  • Updated utilities to version 5.0.7.

New in SearchGUI 4.0.17 (Jan 27, 2021)

  • FEATURE IMPROVEMENT: Updated MetaMorpheus to version 0.0.313.

New in SearchGUI 4.0.13 (Jan 27, 2021)

  • FEATURE IMPROVEMENT:
  • Updated MetaMorpheus to version 0.0.312.

New in SearchGUI 4.0.12 (Jan 12, 2021)

  • FEATURE IMPROVEMENT: The temp folders for Tide can now also be controlled via the search_engine_temp option.

New in SearchGUI 4.0.11 (Jan 11, 2021)

  • FEATURE IMPROVEMENT:
  • The temp folder for OMSSA can now also be controlled via the new search_engine_temp option.

New in SearchGUI 4.0.10 (Jan 7, 2021)

  • FEATURE IMPROVEMENT: The temp folder for OMSSA can now also be controlled via the new search_engine_temp option.

New in SearchGUI 4.0.8 (Jan 6, 2021)

  • BUG FIX: Fixed an issue with indexing mgf files with empty spectra.
  • LIBRARY UPDATE: Updated utilities to version 5.0.4.

New in SearchGUI 4.0.7 (Dec 19, 2020)

  • FEATURE IMPROVEMENT: Updated Comet to version 2020.01 rev. 1.
  • BUG FIX: Fixed an issue with checking for new versions when running in Conda.
  • LIBRARY UPDATE: Updated utilities to version 5.0.3.

New in SearchGUI 4.0.5 (Dec 18, 2020)

  • BUG FIX: Fixed a bug in the Whole Protein digestion for Tide.

New in SearchGUI 4.0.4 (Nov 26, 2020)

  • FEATURE IMPROVEMENT: Added support for parsing spectrum titles with leading or trailing white space.
  • LIBRARY UPDATE: Updated utilities to version 5.0.1.

New in SearchGUI 4.0.3 (Nov 20, 2020)

  • FEATURE IMPROVEMENT: Updated Comet to version 2020.01 rev. 0.

New in SearchGUI 4.0.2 (Nov 10, 2020)

  • BUG FIX: Fixed a bug with a missing temp folder for Andromeda.

New in SearchGUI 4.0.1 (Nov 6, 2020)

  • FEATURE IMPROVEMENT: Added a missing underscore when naming the SearchGUI output file.

New in SearchGUI 4.0.0 (Nov 6, 2020)

  • NEW FEATURE: Added support for MetaMorpheus (version 0.0.312).
  • NEW FEATURE: Added support for spectrum files in mzML format.
  • NEW FEATURE: Added ThermoRawFileParser for support for Thermo raw file conversion.
  • NEW FEATURE: The user can now edit the enzymes via the graphical user interface.
  • FEATURE IMPROVEMENT: Updated MS-GF+ to version 2020.08.05.
  • FEATURE IMPROVEMENT: Updated Comet to version 2019.01 rev. 5.
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 2.0.0.14828.
  • FEATURE IMPROVEMENT: Moved the FASTA file out of the search parameters.
  • FEATURE IMPROVEMENT: Search and de novo engines results are now gzipped upon completion.
  • FEATURE IMPROVEMENT: Added support for TMTpro (i.e. TMT 16-plex).
  • FEATURE IMPROVEMENT: Added support for the X! Tandem parameter “spectrum, parent monoisotopic mass isotope error”, previously hard coded to “yes”.
  • FEATURE IMPROVEMENT: Updated Ensembl to version 101 and Ensembl Genomes to version 48.
  • FEATURE IMPROVEMENT: Refactored the command lines.
  • FEATURE IMPROVEMENT: Moved the code to Java 14. Note that Java 9 or newer is now required to run SearchGUI.
  • FEATURE IMPROVEMENT: The time stamp is now also included in the PeptideShaker output file name (if selected in the advanced settings).
  • FEATURE IMPROVEMENT: The last user selected spectrum and output folders are now remembered in the same way as the FASTA file folder.
  • FEATURE IMPROVEMENT: Added support for parsing the new NCBI FASTA headers.
  • FEATURE IMPROVEMENT: Added taxonomy name to the protein export options.
  • FEATURE IMPROVEMENT: Added coverage including the non-validated peptides to the protein export options.
  • BUG FIX: Fixed a bug with unspecific searches and missed cleavages for MS Amanda.
  • BUG FIX: Better handling of exceptions thrown if MyriMatch runs out of symbols to represent variable modifications.
  • LIBRARY UPDATE: Updated jsparklines to version 1.0.12.
  • LIBRARY UPDATE: Updated junit to version 4.13.1.
  • LIBRARY UPDATE: Updated utilities to version 5.0.0.

New in SearchGUI 3.3.20 (Oct 13, 2020)

  • BUG FIX: Fixed a bug in raw file searches that could occur if running two or more searches in a row without closing the tool.

New in SearchGUI 3.3.19 (May 9, 2020)

  • BUG FIX: Fixed a bug in the OmssaParametersDialog where setIntensityCutOffIncrement was used instead of setMinPeaks.
  • LIBRARY UPDATE: Updated utilities to version 4.12.16.

New in SearchGUI 3.3.18 (May 1, 2020)

  • BUG FIX: Fixed a bug in setting up unspecific searches for X! Tandem.

New in SearchGUI 3.3.17 (May 1, 2020)

  • FEATURE IMPROVEMENT: Fixed mono path issue with Mac OSX El Capitan (10.11) and later.

New in SearchGUI 3.3.16 (Jul 7, 2019)

  • BUG FIX: Fixed a bug in the use of user-defined terminal PTMs.
  • LIBRARY UPDATE: Updated utilities to version 4.12.14.

New in SearchGUI 3.3.14 (May 8, 2019)

  • NEW FEATURE: Added a new command line option -output_default_name that provides better control over the default name of the output files.

New in SearchGUI 3.3.13 (Feb 1, 2019)

  • NEW FEATURE: Added a new command line option -output_default_name that provides better control over the default name of the output files.

New in SearchGUI 3.3.12 (Jan 17, 2019)

  • FEATURE IMPROVEMENT: The user is now referred to the log file if an error occurs when running FastaCLI.

New in SearchGUI 3.3.11 (Dec 17, 2018)

  • FEATURE IMPROVEMENT:
  • Updated the help pages and the SearchGUI reference.

New in SearchGUI 3.3.10 (Dec 13, 2018)

  • FEATURE IMPROVEMENT: Updated Comet to version 2018.01 rev. 3.
  • FEATURE IMPROVEMENT: Included the path to the log file in the error message printed if the command line fails.

New in SearchGUI 3.3.9 (Nov 19, 2018)

  • FEATURE IMPROVEMENT: Added support for hyperplexing combining SILAC and TMT.
  • LIBRARY UPDATE: Updated utilities to version 4.12.13.

New in SearchGUI 3.3.8 (Nov 14, 2018)

  • FEATURE IMPROVEMENT: Added support for Iron atoms.
  • FEATURE IMPROVEMENT: Added support for iodoTMT.
  • FEATURE IMPROVEMENT: Added Heme B as a default PTM.
  • LIBRARY UPDATE: Updated utilities to version 4.12.12.

New in SearchGUI 3.3.7 (Nov 10, 2018)

  • BUG FIX: Fixed issues with http/https when accessing UniProt.
  • LIBRARY UPDATE: Updated utilities to version 4.12.10.

New in SearchGUI 3.3.6 (Nov 6, 2018)

  • FEATURE IMPROVEMENT:
  • Added support for TMT 11-plex.
  • LIBRARY UPDATE:
  • Updated utilities to version 4.12.10.

New in SearchGUI 3.3.4 (Sep 24, 2018)

  • FEATURE IMPROVEMENT: Updated Comet to 2018.01 rev. 2.
  • LIBRARY UPDATE: Updated utilities to version 4.12.8.

New in SearchGUI 3.3.1 (May 10, 2018)

  • FEATURE IMPROVEMENT: MyriMatch now supports terminal modifications at specific amino acids.
  • FEATURE IMPROVEMENT: Updated the links to the MyriMatch web page.

New in SearchGUI 3.3.0 (May 8, 2018)

  • FEATURE IMPROVEMENT: Updated MS-GF+ to v2018.04.09.
  • FEATURE IMPROVEMENT: Updated Comet to v2018.01.
  • LIBRARY UPDATE: Updated utilities to version 4.12.6.

New in SearchGUI 3.2.26 (May 3, 2018)

  • BUG FIX: Fixed a bug in the search setting dialog regarding the use of semi-specific enzymes.
  • LIBRARY UPDATE: Updated utilities to version 4.12.5.

New in SearchGUI 3.2.25 (Apr 28, 2018)

  • BUG FIX: Fixed a bug in the IdentificationParametersInputBean where a break was missing when setting the cleavage preferences for MS-GF+ and MyriMatch..
  • BUG FIX: Fixed a bug where upper case mgf file endings resulted in a null pointer when indexing such files.
  • LIBRARY UPDATE: Updated utilities to version 4.12.4.

New in SearchGUI 3.2.23 (Apr 13, 2018)

  • FEATURE IMPROVEMENT: New Myrimatch Linux 64 version.
  • FEATURE IMPROVEMENT: Updated Comet to release 2017.01 rev. 3.
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 2.0.0.9695 for Windows and version 2.0.0.9706 for Linux/Mac.
  • BUG FIX: Corrected the Andromeda parsing rule to work with RefSeq headers.
  • BUG FIX: Fixed typos in the mzIdentML and Percolator output format file names for Tide.
  • LIBRARY UPDATE: Updated utilities to version 4.12.1.

New in SearchGUI 3.2.22 (Apr 13, 2018)

  • FEATURE IMPROVEMENT: New Myrimatch Linux 64 version.
  • FEATURE IMPROVEMENT: Updated Comet to release 2017.01 rev. 3.
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 2.0.0.9695 for Windows and version 2.0.0.9706 for Linux/Mac.
  • BUG FIX: Corrected the Andromeda parsing rule to work with RefSeq headers.
  • BUG FIX: Fixed typos in the mzIdentML and Percolator output format file names for Tide.
  • LIBRARY UPDATE: Updated utilities to version 4.12.1.

New in SearchGUI 3.2.20 (Jul 19, 2017)

  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 36.
  • LIBRARY UPDATE: Updated utilities to version 4.11.17.

New in SearchGUI 3.2.13 (Apr 3, 2017)

  • BUG FIX: Fixed a problem that corrupted the previous release.

New in SearchGUI 3.2.12 (Apr 3, 2017)

  • FEATURE IMPROVEMENT: Updated Ensembl to version 88.
  • LIBRARY UPDATE: Updated JSparklines to version 1.0.9.
  • LIBRARY UPDATE: Updated utilities to version 4.11.5.

New in SearchGUI 3.2.11 (Mar 20, 2017)

  • BUG FIX: Fixed bugs in the set up of the identification parameters from the command line.
  • LIBRARY UPDATE: Updated utilities to version 4.11.4.

New in SearchGUI 3.2.10 (Mar 7, 2017)

  • BUG FIX: Fixed bugs in the setting of the location of DirecTag and Novor, where the Andromeda location was set instead.
  • BUG FIX: Ensured that the OMSSA modification files are the same for all platforms.

New in SearchGUI 3.2.9 (Mar 3, 2017)

  • BUG FIX: Removed the upper limitation for the number of threads/cores in the Processing Preferences dialog.
  • LIBRARY UPDATE: Updated utilities to version 4.11.2.

New in SearchGUI 3.2.8 (Feb 15, 2017)

  • LIBRARY UPDATE: Updated utilities to version 4.11.2.

New in SearchGUI 3.2.7 (Feb 8, 2017)

  • LIBRARY UPDATE: Updated utilities to version 4.11.0.

New in SearchGUI 3.2.6 (Feb 1, 2017)

  • LIBRARY UPDATE: Updated utilities to version 4.10.0.

New in SearchGUI 3.2.5 (Dec 22, 2016)

  • BUG FIX: Fixed bugs in the use of unspecific and whole protein as the digestion method.
  • LIBRARY UPDATE: Updated utilities to version 4.8.9.

New in SearchGUI 3.2.4 (Dec 22, 2016)

  • BUG FIX: Fixed bugs in the IdentificationParametersInputBean for checking the isotope range where negative values were not allowed.
  • LIBRARY UPDATE: Updated utilities to version 4.8.8.

New in SearchGUI 3.2.3 (Dec 22, 2016)

  • FEATURE IMPROVEMENT: Updated Ensembl to version 87.
  • FEATURE IMPROVEMENT: Updated Ensembl genomes to version 34.
  • BUG FIX: Fixed a bug in the command line setting of the missed cleavages and specificity.
  • BUG FIX: Fixed null pointers in the process builders when using unspecific and whole protein searches.
  • LIBRARY UPDATE: Updated utilities to version 4.8.7.

New in SearchGUI 3.2.2 (Dec 7, 2016)

  • BUG FIX: Fixed a bug in the use of unspecific enzyme in the search settings dialog.
  • LIBRARY UPDATE: Updated utilities to version 4.8.6.

New in SearchGUI 3.2.1 (Dec 5, 2016)

  • BUG FIX: Fixed the backwards compatibility.
  • LIBRARY UPDATE: Updated utilities to version 4.8.5.

New in SearchGUI 3.2.0 (Dec 5, 2016)

  • NEW FEATURE: Added the Fluorine atom as an option when creating custom PTMs.
  • FEATURE IMPROVEMENT: Extended and simplified the enzyme support.
  • FEATURE IMPROVEMENT: Improved the use of the cache.
  • FEATURE IMPROVEMENT: Updated Ensembl genomes to version 33.
  • FEATURE IMPROVEMENT: Improved the handling of the exception encountered when attempting to index too large databases.
  • LIBRARY UPDATE: Updated utilities to version 4.8.4.

New in SearchGUI 3.1.4 (Oct 10, 2016)

  • LIBRARY UPDATE: Updated utilities to version 4.7.5.

New in SearchGUI 3.1.3 (Oct 6, 2016)

  • FEATURE IMPROVEMENT: Updated Ensembl to version 86.
  • LIBRARY UPDATE: Updated utilities to version 4.7.4.

New in SearchGUI 3.1.2 (Oct 6, 2016)

  • BUG FIX: Made sure that the log parameter is recognized when using the command line.
  • LIBRARY UPDATE: Updated utilities to version 4.7.3.

New in SearchGUI 3.1.1 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: User-defined PTMs are now supported when running Andromeda.
  • LIBRARY UPDATE: Updated utilities to version 4.7.2.

New in SearchGUI 3.1.0 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: Updated Tide to version 3.0.17109, which now supports the use of multiple threads/cores.
  • LIBRARY UPDATE: Updated utilities to version 4.7.1.

New in SearchGUI 3.0.4 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: Updated GO and gene mappings to Ensembl 85 and 32.
  • BUG FIX: Fixed a bug in FastaCLI that could result in a HeadlessException.
  • LIBRARY UPDATE: Updated utilities to version 4.7.0.

New in SearchGUI 3.0.3 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: Fixed an issue in the mgf reader where lines ending with r could cause problems.
  • LIBRARY UPDATE: Updated utilities to version 4.6.3.

New in SearchGUI 3.0.2 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: All search engines and de novo algorithms are now turned off by default (both in the GUI and on the command line).

New in SearchGUI 3.0.1 (Sep 14, 2016)

  • BUG FIX: Corrected errors in the command line documentation and parameter testing.
  • LIBRARY UPDATE: Updated utilities to version 4.6.2.

New in SearchGUI 3.0.0 (Sep 14, 2016)

  • NEW FEATURE: Added support for running Novor and DirecTag. (beta)
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.7503 for Windows and version 1.0.0.7504 for Linux/Mac.
  • FEATURE IMPROVEMENT: Added the path settings to the FastaCLI.
  • LIBRARY UPDATE: Updated utilities to version 4.6.1.

New in SearchGUI 2.9.0 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: Updated the Comet version with a minor patch that supports longer spectrum titles in mgf files.
  • FEATURE IMPROVEMENT: Added support for setting the Andromeda decoy mode (reverse or none, none is the new default).
  • FEATURE IMPROVEMENT: Made it possible to set the Comet output type via the command line.
  • FEATURE IMPROVEMENT: Changed the default precursor mass range for Comet and MyriMatch to 600 - 5000.
  • BUG FIX: Fixed a bug in the SearchGUI to PeptideShaker link where there was a bug in the PeptideShaker command line.
  • BUG FIX: Fixed a bug in the output zipping per mgf file, where all the mgfs were added to each zip file.
  • BUG FIX: Corrected the icon used in the privacy settings dialog.
  • LIBRARY UPDATE: Updated utilities to version 4.5.20.

New in SearchGUI 2.8.6 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: The number of missed cleavages when using the unspecific enzyme in X! Tandem is no longer hard coded to 50 but rather the user setting is used.
  • LIBRARY UPDATE: Updated utilities to version 4.5.17.

New in SearchGUI 2.8.5 (Sep 14, 2016)

  • FEATURE IMPROVEMENT: Removed the advanced option of generating the protein index at the same time as running the searches, as this could result in issues. (Note that this removes the protein_index option from the command line.)
  • BUG FIX: Corrected a bug in the setting of the precursor mass filter.
  • LIBRARY UPDATE: Updated utilities to version 4.5.16.

New in SearchGUI 2.8.4 (Apr 21, 2016)

  • BUG FIX: Fixed a bug in the Advanced Settings dialog for setting the max size of the mgf files before splitting.

New in SearchGUI 2.8.3 (Apr 21, 2016)

  • BUG FIX: Minor correction in the command line documentation for the import_precurosor_mz and import_precurosor_mz_ppm parameters
  • LIBRARY UPDATE: Updated utilities to version 4.5.12

New in SearchGUI 2.8.2 (Apr 21, 2016)

  • FEATURE IMPROVEMENT: Updated Comet to version 2016.01 rev. 2
  • LIBRARY UPDATE: Updated utilities to version 4.5.11

New in SearchGUI 2.8.1 (Apr 21, 2016)

  • FEATURE IMPROVEMENT: Updated Comet to version 2016.01 rev. 1.
  • BUG FIX: Fixed bugs in the modification type for “Dimethylation of peptide N-term 2H(4)” and “Dimethylation of peptide N-term”.
  • LIBRARY UPDATE: Updated utilities to version 4.5.8.

New in SearchGUI 2.8.0 (Apr 21, 2016)

  • NEW FEATURE: Added a check for missing precursor charges when parsing mgf files, and the option of adding them. All controlled via the Advanced Settings.
  • FEATURE IMPROVEMENT: Updated Comet to version 2016.01 rev. 0.
  • For details, please see: http://comet-ms.sourceforge.net/release/release_201601/.
  • FEATURE IMPROVEMENT: The Advanced Settings are now saved between each time one runs SearchGUI.
  • FEATURE IMPROVEMENT: Added new PTM: Dimethylation of K 2H(6) 13C(2), also corrected “Dimethylation of peptide N-term K” to “Dimethylation of peptide N-term” and “Dimethylation of peptide N-term K 2H4” to “Dimethylation of peptide N-term 2H4”.
  • FEATURE IMPROVEMENT: Updated the Ensembl mappings to version 84.
  • BUG FIX: Fixed bugs in the validation of the following parameters when given as input on the command line: IMPORT_PRECURSOR_MZ_PPM, PREC_PPM, FRAG_PPM. Note that that the input is now binary (0 for Da and 1 for ppm, instead of 2 for Da and 1 for ppm as before).
  • BUG FIX: Fixed a bug in the PTM dialog where empty patterns were not handled correctly for user defined PTMs.
  • BUG FIX: Fixed a bug in the background color for the drop down menus with tooltips.
  • LIBRARY UPDATE: Updated jsparklines to version 1.0.8.
  • LIBRARY UPDATE: Updated utilities to version 4.5.7.

New in SearchGUI 2.7.1 (Apr 21, 2016)

  • FEATURE IMPROVEMENT: Updated the default PTM localization settings.
  • BUG FIX: Correction in the iTRAQ 4-plex 115 mass.
  • BUG FIX: It is now possible to open the ProteinInferenceSettingsDialog even if the FASTA file is not set.
  • BUG FIX: Fixed a bug in the isSameAs method in PeptideAssumptionFilter.
  • BUG FIX: The check for comma in PTM names now actually works.
  • LIBRARY UPDATE: Updated utilities to version 4.5.3.

New in SearchGUI 2.7.0 (Apr 21, 2016)

  • FEATURE IMPROVEMENT: Updated X!Tandem to version VENGEANCE (2015.12.15)
  • Note that X!Tandem no longer releases 32 bit versions, only the 64 bit versions will be updated from now on
  • FEATURE IMPROVEMENT: Extended the list of supported output formats for Comet
  • FEATURE IMPROVEMENT: ProteoWizard is now shown as supported on all platforms (but converting vendor raw files is still only supported in Windows)
  • BUG FIX: Improved the test for checking if a user selected Java home folder contains a valid Java installation or not
  • LIBRARY UPDATE: Updated utilities to version 4.3.22

New in SearchGUI 2.6.5 (Feb 12, 2016)

  • BUG FIX: Minor correction in the command line documentation for the comet_num_ptms option.
  • BUG FIX: Corrected an error in the definition of the iTRAQ 8plex 115 ion.
  • BUG FIX: Made sure that the variable PTM names are checked (for if a PTM with that name exists) when setting up the identification parameters from the command line (the fixed PTM names were already checked).
  • BUG FIX: Fixed a bug in the ProteinInferencePreferences that resulted in a null pointer if the database was not set (for example when the parameter file was created in DeNovoGUI).
  • BUG FIX: Fixed a bug in the command line for displaying the list of supported PTMs, where the -out parameter was required.
  • BUG FIX: Renamed the PTM “Dimethylation of K 2H(4)” to “Label of K 2H(4)”.
  • LIBRARY UPDATE: Updated utilities to version 4.3.22.

New in SearchGUI 2.6.4 (Feb 12, 2016)

  • FEATURE IMPROVEMENT: If the user cancels a partial search (in the GUI) the user is now asked if he/she wants to keep the partial search results (instead of automatic removal as before).

New in SearchGUI 2.6.3 (Feb 12, 2016)

  • BUG FIX: Fixed a bug in the mass deviation filter where min and max isotope had gotten mixed up.
  • LIBRARY UPDATE: Updated utilities to version 4.3.21.

New in SearchGUI 2.6.2 (Feb 6, 2016)

  • BUG FIX: Fixed a bug in the loading of the user PTMs in the SearchSettingsDialog.
  • BUG FIX: The PTM Dialog now checks if reporter ion and neutral loss names are unique before adding them.
  • BUG FIX: Fixed a bug in the PTM Dialog where user defined neutral losses where always of type fixed.
  • BUG FIX: Changed the default for the MyriMatch MaxPeakCount parameter back to the default of 300.
  • LIBRARY UPDATE: Updated jsparklines to version 1.0.7.
  • LIBRARY UPDATE: Updated utilities to version 4.3.20.

New in SearchGUI 2.6.1 (Feb 6, 2016)

  • FEATURE IMPROVEMENT: Added support for Arg-N.
  • FEATURE IMPROVEMENT: Updated the Andromeda web page link.
  • LIBRARY UPDATE: Updated utilities to version 4.3.18.

New in SearchGUI 2.6.0 (Jan 27, 2016)

  • FEATURE IMPROVEMENT: Updated MS Amanda to version v1.0.0.6299 for Windows and version v1.0.0.6300 for Linux and Mac.
  • FEATURE IMPROVEMENT: Added support for setting the X!Tandem output type (all, valid, stochastic).
  • BUG FIX: Fixed a bug in the X!Tandem and Tide enzyme setup for enzymes with no restriction amino acids.
  • LIBRARY UPDATE: Updated utilities to version 4.3.17.

New in SearchGUI 2.5.0 (Jan 27, 2016)

  • FEATURE IMPROVEMENT: Updated Comet to release 2015.02 rev. 5, improving the mgf parsing.
  • FEATURE IMPROVEMENT: Added support for Semi-GluC-(DE).
  • BUG FIX: Fixed an issue that resulted in the tool not starting if a custom Java home was set and it could not be found.
  • BUG FIX: Fixed a bug in the command line where the parameter file was not added correctly to the zipped output file.
  • LIBRARY UPDATE: Updated utilities to version 4.3.16.

New in SearchGUI 2.4.1 (Jan 18, 2016)

  • BUG FIX: Fixed a bug in the use of the time stamp for the zip file output.

New in SearchGUI 2.4.0 (Jan 15, 2016)

  • FEATURE IMPROVEMENT: Updated Tide to version 2.1.16872, adding a 64 bit version for Windows that is both faster and able to handle bigger FASTA files.
  • BUG FIX: Fixed a bug in the advanced settings dialog where the zipping options were not displayed correctly upon reopening the dialog.
  • LIBRARY UPDATE: Updated utilities to version 4.3.11.

New in SearchGUI 2.3.2 (Jan 4, 2016)

  • NEW FEATURE: Added import filter for the number of missed cleavages for the peptides when loading in PeptideShaker.
  • FEATURE IMPROVEMENT: Updated the ISAS logo in the splash screen.
  • FEATURE IMPROVEMENT: Removed an unnecessary white space in the modification tag in the MS Amanda settings file.
  • FEATURE IMPROVEMENT: Made sure that the 24 hour format is used in all time stamps.
  • FEATURE IMPROVEMENT: Improved the formatting of the file names for the advanced zipping output options.
  • LIBRARY UPDATE: Updated utilities to version 4.3.5.

New in SearchGUI 2.3.1 (Dec 29, 2015)

  • BUG FIX: Fixed a bug in the creation of an identification settings file via the GUI.
  • LIBRARY UPDATE: Updated utilities to version 4.3.4.

New in SearchGUI 2.3.0 (Dec 29, 2015)

  • NEW FEATURE: A log folder can now be selected when operating in command line.
  • FEATURE IMPROVEMENT: The isotopic correction is now part of the main search parameters.
  • FEATURE IMPROVEMENT: First attempt at supporting fragment ion tolerance in ppm.
  • FEATURE IMPROVEMENT: Added support for Semi-Arg-C.
  • FEATURE IMPROVEMENT: The mgf file is now given to Comet directly.
  • FEATURE IMPROVEMENT: Updated the Ensembl mappings to version 83.
  • FEATURE IMPROVEMENT: Updated the Ensembl Genomes mapping to version 30.
  • FEATURE IMPROVEMENT: Corrected the names used for the enzymatic cleavage types in the Comet Advanced Settings dialog (according to corrected documentation for Comet).
  • BUG FIX: Fixed a bug in the MS Amanda setup where the highest charge in the selected range was not added, e.g. [2-4] became [2-3].
  • BUG FIX: Fixed an error in the “Thermolysin, no P rule” enzyme, where the P rule was actually added.
  • BUG FIX: The MS Amanda enzyme file is now generated each time MS Amanda is run, and now supports all enzymes (except Asp-N + Glu-C).
  • BUG FIX: Corrected issues in the Formic Acid and Trypsin + Glu-C enzymes for MS Amanda.
  • BUG FIX: Added a fix for a Java bug where the button for the scroll bar could disappear on certain Java versions.
  • BUG FIX: The UniProt taxonomy mapping is now loaded before working with the identification parameters avoiding a null pointer when loading files containing search parameters only.
  • BUG FIX: Fixed a bug where the identification parameters file was not set in SearchCLI.
  • BUG FIX: Fix the saving of the advanced settings for search engines so that the general search settings are not reset.
  • LIBRARY UPDATE: Updated utilities to version 4.3.3.

New in SearchGUI 2.2.2 (Dec 8, 2015)

  • BUG FIX: Fixed a bug in the MS-GF+ enzyme mapping for GluC.
  • LIBRARY UPDATE: Updated utilities to version 4.1.15.

New in SearchGUI 2.2.1 (Dec 7, 2015)

  • FEATURE IMPROVEMENT: Added support for new enzyme: Trypsin + Glu-C.
  • BUG FIX: Fixed a bug where Andromeda changed the general enzyme properties when settings up its own enzymes.
  • LIBRARY UPDATE: Updated utilities to version 4.1.13.

New in SearchGUI 2.2.0 (Dec 7, 2015)

  • FEATURE IMPROVEMENT: Updated Comet to version 2015.02 rev. 3.
  • FEATURE IMPROVEMENT: Support for LysargiNase and extended enzyme support for MyriMatch and MS-GF+.
  • FEATURE IMPROVEMENT: Added support for partial digest for Andromeda.
  • FEATURE IMPROVEMENT: Partial digest is now set for Tide based on the enzyme selected.
  • FEATURE IMPROVEMENT: Updated the parameters related classes to work with json files.
  • FEATURE IMPROVEMENT: Changed the X!Tandem and OMSSA logos to be the same format as the other logos.
  • BUG FIX: Fixed a bug that affected variable n-term modification without specific targets when running Comet.
  • LIBRARY UPDATE: Updated utilities to version 4.1.13.

New in SearchGUI 2.1.4 (Oct 22, 2015)

  • BUG FIX: Made the tool work on Java 1.6 again.
  • LIBRARY UPDATE: Updated utilities to version 4.1.8.

New in SearchGUI 2.1.3 (Oct 17, 2015)

  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 29.
  • LIBRARY UPDATE: Updated utilities to version 4.1.1.

New in SearchGUI 2.1.2 (Oct 15, 2015)

  • BUG FIX: Fixed a bug in the mgf splitting.

New in SearchGUI 2.1.1 (Oct 14, 2015)

  • FEATURE IMPROVEMENT: Enabled the multithreading for msconvert.
  • FEATURE IMPROVEMENT: Made it possible to cancel msconvert processes.
  • FEATURE IMPROVEMENT: Prevented processes from starting in case the search has been cancelled.
  • LIBRARY UPDATE: Updated utilities to version 4.0.15.

New in SearchGUI 2.1.0 (Oct 13, 2015)

  • FEATURE IMPROVEMENT: The Andromeda temp folder is only deleted once all mgf files have been searched.
  • FEATURE IMPROVEMENT: Cleaned up the handling of exceptions to avoid printing stack traces.
  • LIBRARY UPDATE: Updated utilities to version 4.0.14.

New in SearchGUI 2.0.11 (Oct 4, 2015)

  • BUG FIX: Fixed a possible null pointer related to PTMs not targeting specific amino acids when setting up X!Tandem searches.
  • BUG FIX: Fixed a bug in the mgf parser where comments between the peak lists was not supported.
  • LIBRARY UPDATE: Updated utilities to version 4.0.13.

New in SearchGUI 2.0.10 (Oct 2, 2015)

  • BUG FIX: Fixed bugs in the search parameters where the advanced search engine settings had gone missing.
  • LIBRARY UPDATE: Updated utilities to version 4.0.12.

New in SearchGUI 2.0.9 (Oct 2, 2015)

  • FEATURE IMPROVEMENT: Improved how some of the dialogs resize in low screen resolution conditions.
  • LIBRARY UPDATE: Updated utilities to version 4.0.11.

New in SearchGUI 2.0.8 (Oct 1, 2015)

  • FEATURE IMPROVEMENT: Updated Comet to version 2015.02 rev. 1.
  • FEATURE IMPROVEMENT: Updated Ensembl to version 82.
  • LIBRARY UPDATE: Updated utilities to version 4.0.10.

New in SearchGUI 2.0.7 (Sep 28, 2015)

  • FEATURE IMPROVEMENT: Added a command line option (-fasta) that makes it possible to override the FASTA file location in the search parameter file used.

New in SearchGUI 2.0.6 (Sep 24, 2015)

  • BUG FIX: Improved the handling of the advanced search engine settings in the search parameters.
  • LIBRARY UPDATE: Updated utilities to version 4.0.8.

New in SearchGUI 2.0.5 (Sep 18, 2015)

  • BUG FIX: Fixed a bug in the Comet command line that occurred when a non-standard Comet temp folder was used.
  • LIBRARY UPDATE: Updated jsparklines to version 1.0.6.
  • LIBRARY UPDATE: Updated utilities to version 4.0.5.

New in SearchGUI 2.0.4 (Sep 5, 2015)

  • BUG FIX: Another attempt at fixing a bug where the output folder was deleted instead of the temp folder.

New in SearchGUI 2.0.2 (Sep 4, 2015)

  • BUG FIX: Improved the handling of the file path in the search settings files.
  • BUG FIX: Fixed an issue with the wrapper in handling memory warnings for 32 bit Java 8.
  • LIBRARY UPDATE: Updated utilities to version 4.0.4.

New in SearchGUI 2.0.1 (Aug 31, 2015)

  • BUG FIX: Fixed a bug that canceled the command line use.

New in SearchGUI 2.0.0 (Aug 29, 2015)

  • NEW FEATURE: Added support for Andromeda. (beta)
  • NEW FEATURE: PTM masses are now set via the atomic composition.
  • NEW FEATURE: Renamed .cps to .cpsx and .parameters to .par.
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.5242 for Windows and version 1.0.0.5243 for Linux/Mac.
  • Bugfix for n-terminal modifications targeting a specific amino acid.
  • Bugfix for database digestion.
  • Alternative modification site consideration.
  • Performance improvements.
  • FEATURE IMPROVEMENT: Updated Comet to version 2015.02 rev. 0.
  • FEATURE IMPROVEMENT: The user is now asked if the settings should be saved if the advanced search engine settings are changed.
  • FEATURE IMPROVEMENT: The Tide enzyme parameter is now mapped to the Tide enzyme name if possible (to ensure compatibility with TPP when exporting as pepxml.)
  • FEATURE IMPROVEMENT: Updated Ensembl to version 81.
  • BUG FIX: Fixed bugs in PathSettingsCLI where the paths could not be set.
  • BUG FIX: Corrected an error that could occur when working with raw files.
  • BUG FIX: Corrected an error in the handling of filters options for msconvert.
  • LIBRARY UPDATE: Updated utilities to version 4.0.0.

New in SearchGUI 1.30.1 (Jul 1, 2015)

  • BUG FIX: Removed test code.

New in SearchGUI 1.30.0 (Jun 30, 2015)

  • NEW FEATURE: Added support for raw files as input to SearchGUI via PRIDE Reshake.
  • FEATURE IMPROVEMENT: Reduced the height of the SearchGUI main dialog to better fit on smaller screens.
  • LIBRARY UPDATE: Updated utilities to version 3.49.21.

New in SearchGUI 1.29.0 (Jun 22, 2015)

  • NEW FEATURE: Added pre-processing of raw files using msConvert.
  • FEATURE IMPROVEMENT: Fixed a backwards compatibility issue with the search settings.
  • BUG FIX: Fixed a bug in the GO mappings that resulted from a change in the Ensembl BioMart.
  • LIBRARY UPDATE: Updated utilities to version 3.49.19.

New in SearchGUI 1.28.1 (Jun 11, 2015)

  • LIBRARY UPDATE: Updated utilities to version 3.49.7.

New in SearchGUI 1.28.0 (Jun 11, 2015)

  • FEATURE IMPROVEMENT: Updated the Ensembl mappings to Ensembl 80.
  • FEATURE IMPROVEMENT: Changed the default isotope correction range for MS-GF+ from [0,1] to [-1,2].
  • BUG FIX: Fixed issues with validating some of the OMSSA parameters when used via the command line.
  • LIBRARY UPDATE: Updated utilities to version 3.49.2.

New in SearchGUI 1.27.4 (May 18, 2015)

  • FEATURE IMPROVEMENT: Added support for parsing UniRef headers.
  • LIBRARY UPDATE: Updated utilities to version 3.48.5.

New in SearchGUI 1.27.3 (May 12, 2015)

  • FEATURE IMPROVEMENT: Leading and trailing white space is now removed before parsing FASTA headers.
  • LIBRARY UPDATE: Updated utilities to version 3.48.4.

New in SearchGUI 1.27.2 (Apr 27, 2015)

  • BUG FIX: Corrected bugs in the setting of temporary folders.
  • BUG FIX: Fixed a bug in the CV term mapping for pyro-cmc.
  • LIBRARY UPDATE: Updated utilities to version 3.47.4.

New in SearchGUI 1.27.1 (Apr 27, 2015)

  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.4484 for Windows and version 1.0.0.4458 for Linux/Mac.
  • Fixing an issue with the test for FASTA file file name length.
  • LIBRARY UPDATE: Updated utilities to version 3.46.13.

New in SearchGUI 1.27.0 (Apr 27, 2015)

  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.4456 for Windows and version 1.0.0.4457 for Linux/Mac.
  • Adding a low memory option.
  • Support for mgf files with empty charge tags.
  • Better error message for too long FASTA file names.
  • FEATURE IMPROVEMENT: Updated Comet to version 2015.01 rev. 1.
  • BUG FIX: Fixed a bug in temp folder used for Comet and Tide where the folder was not created if it didn't already exist.
  • BUG FIX: Fixed a bug with the link to the parameter file in the Comet temp folder.
  • BUG FIX: Fixed a bug in the path to X!Tandem when run on Windows in command line mode.
  • BUG FIX: The Tide and Comet results files are now actually moved from the temp folder to the results folder instead of just copied.
  • LIBRARY UPDATE: Updated utilities to version 3.46.12.

New in SearchGUI 1.26.6 (Apr 8, 2015)

  • BUG FIX: Fixed bugs related to running in command line mode on systems without an X11 DISPLAY.

New in SearchGUI 1.26.5 (Mar 27, 2015)

  • FEATURE IMPROVEMENT: Updated the Ensembl mappings to Ensembl 79.
  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 26.
  • BUG FIX: Fixed a typo in the mass for TMT130 report for 6plex TMT.
  • BUG FIX: Fixed backwards compatibility issues in the TideParameters.
  • BUG FIX: Fixed a bug that made it impossible to run Tide and PeptideShaker post-processing at the same time.
  • LIBRARY UPDATE: Updated utilities to version 3.46.9.

New in SearchGUI 1.26.4 (Mar 12, 2015)

  • FEATURE IMPROVEMENT: Added a check for supported MyriMatch and Tide output formats if PeptideShaker is selected.
  • BUG FIX: Fixed bugs related to the Tide output format not being text.
  • BUG FIX: The enzyme is now set correctly in the Comet pepXML output.
  • BUG FIX: The user selected MyriMatch output format is now actually used.
  • BUG FIX: Corrected a bug in the handling of default paths.
  • LIBRARY UPDATE: Updated utilities to version 3.45.44.

New in SearchGUI 1.26.3 (Feb 21, 2015)

  • BUG FIX: The enzyme is now set for Tide, instead of always defaulting to trypsin.
  • BUG FIX: Tide can now be run without any PTMs.
  • BUG FIX: Fixed bugs in the comparison of Tide parameters.
  • LIBRARY UPDATE: Updated utilities to version 3.45.36.

New in SearchGUI 1.26.2 (Feb 18, 2015)

  • BUG FIX: Fixed bugs for the setting of the default search engine locations (for OMSSA and X!Tandem) in the command line mode.

New in SearchGUI 1.26.1 (Feb 18, 2015)

  • BUG FIX: Renamed the default X!Tandem folder into XTandem, as '!' is not allowed in paths on Linux.
  • LIBRARY UPDATE: Updated utilities to version 3.45.35.

New in SearchGUI 1.26.0 (Feb 17, 2015)

  • FEATURE IMPROVEMENT: Fixed an issue with using high resolution data in Tide. (Could also affect Comet results.)
  • LIBRARY UPDATE: Updated utilities to version 3.45.33.

New in SearchGUI 1.25.7 (Feb 12, 2015)

  • FEATURE IMPROVEMENT: Improved the command line error handling.
  • BUG FIX: Fixed a bug in the CV term name for TMT6plex, hindering the use of TMT 6-plex (and 10-plex) in MS Amanda.
  • LIBRARY UPDATE: Updated utilities to version 3.45.32.

New in SearchGUI 1.25.6 (Feb 5, 2015)

  • BUG FIX: Fixed a bug where the adding of decoys also removed the target sequences.

New in SearchGUI 1.25.5 (Feb 3, 2015)

  • BUG FIX: Removed GUI code from the process builders.

New in SearchGUI 1.25.4 (Jan 30, 2015)

  • BUG FIX: Corrected the default paths to the search engines.

New in SearchGUI 1.25.3 (Jan 30, 2015)

  • BUG FIX: The command line now works again.

New in SearchGUI 1.25.2 (Jan 30, 2015)

  • BUG FIX: Fixed a bug where neutral losses and reporter ions for user defined modifications disappeared.
  • LIBRARY UPDATE: Updated utilities to version 3.45.25.

New in SearchGUI 1.25.1 (Jan 29, 2015)

  • NEW FEATURE: Added pepXML as an output option for OMSSA.
  • FEATURE IMPROVEMENT: User modifications are now also mapped to Unimod for MS Amanda.
  • FEATURE IMPROVEMENT: Made it possible to automatically remove the Tide temp folders when a Tide search is complete.
  • LIBRARY UPDATE: Updated utilities to version 3.45.24.

New in SearchGUI 1.25.0 (Jan 23, 2015)

  • NEW FEATURE: Added support for Tide. (beta)
  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.3948 for Windows and 1.0.0.3947 for Linux/Mac:
  • New weighted probability/e-value in the output.
  • Bugfix for whole protein/already digested databases.
  • Bugfix for decoy database creation.
  • Bugfix for water/ammonia loss consideration.
  • FEATURE IMPROVEMENT: PTMs are now given as Unimod for MS Amanda, which improves the PSMs.
  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 25.
  • LIBRARY UPDATE: Updated utilities to version 3.45.19.

New in SearchGUI 1.24.0 (Jan 20, 2015)

  • FEATURE IMPROVEMENT: Updated MS-GF+ to version "Beta (v10282) (12/19/2014)":
  • Fixing an issue with parsing mgf files where scan numbers are not numbers.
  • Improves the multi threaded performance.
  • Fixing a bug that occurs when C-term mod mass is below -57Da.
  • Adds a test that checks whether the output path is valid before processing the data.
  • FEATURE IMPROVEMENT: Updated the gene and GO mappings to Ensembl version 78.
  • FEATURE IMPROVEMENT: Added quotes around the species type in the PeptideShaker command line.
  • FEATURE IMPROVEMENT: The search engine installation error dialog is now actually shown if a search engine fails the startup test, and the dialog now includes links to the trouble shooting section and to Mono download for MS Amanda on Mac/Linux.
  • FEATURE IMPROVEMENT: Made it possible to set the Java Home from the GUI.
  • FEATURE IMPROVEMENT: Added a dialog to edit the path preferences.
  • BUG FIX: Fixed a bug in the Species Dialog where the text on the Update/Download button was not always correct.
  • LIBRARY UPDATE: Updated utilities to version 3.45.18.

New in SearchGUI 1.23.3 (Nov 28, 2014)

  • FEATURE IMPROVEMENT: Updated MS Amanda to version 1.0.0.3764 for Windows:
  • no output file generated if the search fails
  • bug fix for n-terminal modifications
  • better logging
  • bug fix for FASTA parsing with special identifiers.
  • BUG FIX: Fixed a bug in the conversion of mgf files for use in Comet where scan numbers resulted in it being impossible to map back to the original mgf file.
  • LIBRARY UPDATE: Updated utilities to version 3.43.16.

New in SearchGUI 1.23.2 (Nov 28, 2014)

  • BUG FIX: Fixed a bug in adding decoy sequences to FASTA files containing headers without descriptions.

New in SearchGUI 1.23.1 (Nov 18, 2014)

  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 24, adding Zootermopsis nevadensis.
  • FEATURE IMPROVEMENT: Added a check for if SearchGUI is started from within a zip file.
  • BUG FIX: Fixed a bug in the download of gene mappings for non-vertebrate species.
  • BUG FIX: Fixed some special case Derby shutdown and restart issues.
  • LIBRARY UPDATE: Updated utilities to version 3.43.13.

New in SearchGUI 1.23.0 (Nov 15, 2014)

  • BUG FIX: Fixed a bug in the appending of decoy sequence which in some cases altered the FASTA headers.
  • LIBRARY UPDATE: Updated utilities to version 3.43.10.

New in SearchGUI 1.22.2 (Nov 6, 2014)

  • BUG FIX: Fixed a bug in the handling of variable modifications for X!Tandem.

New in SearchGUI 1.22.1 (Nov 6, 2014)

  • BUG FIX: Fixed a bug in the auto update feature.
  • BUG FIX: Fixed some backward compatibility issues.
  • LIBRARY UPDATE: Updated utilities to version 3.41.1.

New in SearchGUI 1.22.0 (Oct 24, 2014)

  • NEW FEATURE: Added support for Comet.
  • NEW FEATURE: Updated MS Amanda to version 1.0.0.3585:
  • Faster when a high number of variable PTMs are used.
  • Bug fix for lower-case FASTA sequences.
  • Bug fix for different modifications targeting the same amino acid.
  • NEW FEATURE: MS Amanda is now supported on Linux (v1.0.0.3635). (beta). Requires that mono is installed.
  • FEATURE IMPROVEMENT: Updated Ensembl Genomes to version 77, adding Vervet-AGM (Chlorocebus sabaeus).
  • FEATURE IMPROVEMENT: Added progress bar when zipping.
  • FEATURE IMPROVEMENT: The list of database types and their occurrences is now included in the FASTA index.
  • FEATURE IMPROVEMENT: Renamed "no enzyme" to the more understandable "unspecific".
  • FEATURE IMPROVEMENT: Added support for unspecific cleavage for X!Tandem.
  • BUG FIX: Fixed a bug that made it impossible to re-select MyriMatch if it was deselected in the GUI.
  • BUG FIX: Fixed a bug in the use of the Ensembl gene mappings where a field had been renamed in the Ensembl web service.
  • LIBRARY UPDATE: Updated utilities to version 3.40.0.

New in SearchGUI 1.21.0 (Sep 19, 2014)

  • FEATURE IMPROVEMENT: In MyriMatch the MonoisotopeAdjustmentSet parameter is now automatically set to 0 when the MonoPrecursorMzTolerance is wide (as defined by MyriMatch).
  • FEATURE IMPROVEMENT: Added quotation marks so that the MyriMatch, MS-GF+ and MS Amanda command lines printed to the log file can be run directly from the command line.
  • FEATURE IMPROVEMENT: Fixed an issue with indexing mgf files with empty charge tags.
  • LIBRARY UPDATE: Updated jsparklines to version 1.0.4.
  • LIBRARY UPDATE: Updated utilities to version 3.37.3.

New in SearchGUI 1.20.8 (Sep 8, 2014)

  • FEATURE IMPROVEMENT: Improved the parsing of headers of type genome translated to protein sequence.
  • LIBRARY UPDATE: Updated utilities to version 3.35.7.

New in SearchGUI 1.20.7 (Sep 3, 2014)

  • FEATURE IMPROVEMENT: Changed the default PTM localization score to A-score for PeptideShaker.
  • LIBRARY UPDATE: Updated utilities to version 3.35.6.

New in SearchGUI 1.20.6 (Aug 30, 2014)

  • BUG FIX: Fixed a bug with the tooltips for the PTMs in the Search Settings dialogs.
  • BUG FIX: Fixed a bug with the use of custom PTM patterns.
  • LIBRARY UPDATE: Updated utilities to version 3.35.5.

New in SearchGUI 1.20.5 (Aug 30, 2014)

  • FEATURE IMPROVEMENT: Updated Ensembl genomes to release 23.
  • BUG FIX: Fixed an issue in the auto update feature that could occur on specific client machine setups.
  • LIBRARY UPDATE: Updated utilities to version 3.35.3.

New in SearchGUI 1.20.4 (Aug 30, 2014)

  • FEATURE IMPROVEMENT: Several fixes related to running PeptideShaker from SearchGUI.
  • FEATURE IMPROVEMENT: Added MS Amanda settings file to the zip file.
  • LIBRARY UPDATE: Updated utilities to version 3.35.2.

New in SearchGUI 1.20.3 (Aug 8, 2014)

  • NEW FEATURE: Added PTM tooltips in the tables in the SearchSettings dialog.
  • FEATURE IMPROVEMENT: Updated the Ensembl mappings to Ensembl 76 and added seven new species: duck, cave fish, flycatcher, cod, spotted gar, sheep and amazon molly.
  • FEATURE IMPROVEMENT: Improved the species names listed for vertebrates.
  • LIBRARY UPDATE: Updated utilities to version 3.31.2.

New in SearchGUI 1.20.2 (Aug 2, 2014)

  • FEATURE IMPROVEMENT: MyriMatch: Added an HCD option to the fragmentation rules.
  • FEATURE IMPROVEMENT: MyriMatch: Added the MaxPeakCount parameter to the advanced settings.
  • FEATURE IMPROVEMENT: MyriMatch: Added the use of the cpus parameter to set the number of threads/cores used.
  • FEATURE IMPROVEMENT: MyriMatch: ComputeXCorr option now defaults to false, as it is not used in PeptideShaker.
  • FEATURE IMPROVEMENT: MyriMatch: Added support for terminal fixed modifications. (Note that fixed protein terminal modifications and fixed terminal modifications at a given amino acid are not supported, and are therefore treated as variable and later filtered in PeptideShaker.)
  • BUG FIX: Made sure that the zipping is not performed if the search is canceled.
  • LIBRARY UPDATE: Updated utilities to version 3.30.3.

New in SearchGUI 1.20.1 (Aug 1, 2014)

  • FEATURE IMPROVEMENT: Updated the included human gene and GO mappings to Ensembl version 75.
  • FEATURE IMPROVEMENT: Improved the way auto updating of GO and gene mappings are done when starting PeptideShaker from SearchGUI.
  • FEATURE IMPROVEMENT: Reordered the search engines in the main frame and in the SearchEnginesSettingsDialog.
  • LIBRARY UPDATE: Updated utilities to version 3.30.1.

New in SearchGUI 1.20.0 (Jul 30, 2014)

  • NEW FEATURE: Added support for MyriMatch.
  • NEW FEATURE: Added indicators of the supported platforms for each search engine.
  • NEW FEATURE: Added an advanced feature option to zip the search results output.
  • NEW FEATURE: Updated MS Amanda to version 1.0.0.3253, fixing problems with parsing strange retention times in mgf files.
  • FEATURE IMPROVEMENT: Made sure that the PeptideShaker log is saved even if the processing fails.
  • FEATURE IMPROVEMENT: Made sure that closing a dialog is always considered the same as using the cancel button.
  • LIBRARY UPDATE: Updated jsparklines to version 0.8.0.
  • LIBRARY UPDATE: Updated utilities to version 3.29.7.

New in SearchGUI 1.19.5 (Jun 26, 2014)

  • FEATURE IMPROVEMENT: The search engines are now run in the order listed in the GUI.
  • FEATURE IMPROVEMENT: Improved the Unimod cv term mappings.
  • FEATURE IMPROVEMENT: Tried to improve the monitoring of the search engine processes.
  • FEATURE IMPROVEMENT: Improved the Waiting Dialog.
  • FEATURE IMPROVEMENT: Renamed Protein Tree to Protein Index in the Advanced Settings dialog and help text.
  • BUG FIX: Fixed a bug with case sensitivity in the PRIDE PTM mapping.
  • LIBRARY UPDATE: Updated utilities to version 3.28.30.

New in SearchGUI 1.19.4 (Jun 19, 2014)

  • BUG FIX: Fixed a bug in the auto update functionality.

New in SearchGUI 1.19.3 (Jun 18, 2014)

  • BUG FIX: Corrected typos in the help files.
  • BUG FIX: Fixed some typos in the error messages in the CLI.
  • LIBRARY UPDATE: Updated utilities to version 3.28.18.

New in SearchGUI 1.19.2 (Jun 14, 2014)

  • NEW FEATURE: Updated MS Amanda to version 1.0.0.3196, which includes the MS Amanda version in the output file.
  • LIBRARY UPDATE: Updated utilities to version 3.28.16.

New in SearchGUI 1.19.1 (Jun 6, 2014)

  • BUG FIX: Fixed a bug in the parsing of terminal modifications for MS Amanda.
  • BUG FIX: Fixed a bug where MS Amanda results files where not recognized if PeptideShaker was started from SearchGUI.
  • LIBRARY UPDATE: Updated utilities to version 3.28.11.

New in SearchGUI 1.18.7 (May 21, 2014)

  • BUG FIX: Fixed a bug with the gene/GO downloads for non-vertebrate species.
  • LIBRARY UPDATE: Updated utilities to version 3.26.41.

New in SearchGUI 1.18.5 (May 15, 2014)

  • NEW FEATURE: Updated MS-GF+ to version v10024, fixing an issue with using large memory.
  • FEATURE IMPROVEMENT: If SearchGUI is moved (or a parent folder is renamed) the paths to the search engines will be tried reset to the default paths at the new location.
  • BUG FIX: The MS-GF+ and MS Amanda processes are now canceled if the search is canceled.
  • BUG FIX: Fixed a bug in the mgf_splitting option where using large values could break the option and start splitting files smaller than the provided limit.
  • LIBRARY UPDATE: Updated utilities to version 3.26.33.

New in SearchGUI 1.18.4 (May 5, 2014)

  • NEW FEATURE: Made it possible to set the makeblastdb location in the GUI.
  • NEW FEATURE: Added support for 64 bit Linux for makeblastdb.
  • FEATURE IMPROVEMENT: Added an option to makeblastdb that is mandatory in newer versions.
  • BUG FIX: Fixed a bug in the use of non-default install folders for MS Amanda.
  • LIBRARY UPDATE: Updated utilities to version 3.26.30.

New in SearchGUI 1.18.3 (May 3, 2014)

  • NEW FEATURE: Added command line support for setting the makeblastdb folder.
  • NEW FEATURE: Added command line support for setting the decoy suffix tag when adding decoys using FastaCLI.
  • BUG FIX: Fixed a bug in the command line version of MS-GF+ where the search could be canceled if the SearchGUI path was not set.

New in SearchGUI 1.18.2 (Apr 30, 2014)

  • NEW FEATURE: Added new command line options for path configuration.
  • NEW FEATURE: Added an option for turning the protein tree generation on/off from the command line.
  • FEATURE IMPROVEMENT: Added a check and warning if using Java 1.5 or 1.6.
  • FEATURE IMPROVEMENT: Added the possibility for the user to turn on and off the auto update.
  • BUG FIX: Fixed a bug in the processing of the search parameters from the command line where the min charge was set to the same value as the max charge.
  • BUG FIX: Fixed a bug in the PeptideShakerSettingsDialog where the wrong icons was used for the species downloading.
  • LIBRARY UPDATE: Updated utilities to version 3.26.28.

New in SearchGUI 1.18.1 (Apr 14, 2014)

  • BUG FIX: Fixed a bug in the modification mapping for MS Amanda where peptide and protein n terminal modifications were switched.

New in SearchGUI 1.18.0 (Apr 12, 2014)

  • NEW FEATURE: Added support for MS Amanda for Windows (beta).
  • FEATURE IMPROVEMENT: Added the option to turn the protein tree creation on/off in the AdvancedSettings Dialog.
  • BUG FIX: Fixed problems with creating terminal PTMs with empty modification patterns.
  • LIBRARY UPDATE: Updated utilities to version 3.26.14.

New in SearchGUI 1.17.3 (Apr 1, 2014)

  • BUG FIX: Fixed a bug in the peptide to protein mapping where the final protein was not included.
  • LIBRARY UPDATE: Updated utilities to version 3.26.4.

New in SearchGUI 1.17.2 (Mar 28, 2014)

  • NEW FEATURE: Updated MS-GF+ to version MS-GF+ Beta (v9979) (3/26/2014).
  • FEATURE IMPROVEMENT: Improved the error handling when index files cannot be written to during the validation of mgf files.
  • LIBRARY UPDATE: Updated utilities to version 3.25.15.

New in SearchGUI 1.17.0 (Mar 27, 2014)

  • NEW FEATURE: Added support for MS-GF+.
  • BUG FIX: Added a check for "&" in the spectrum, database and output files/folder when X!Tandem is used, as "&" makes the X!Tandem XML input files unreadable.
  • BUG FIX: Fixed a bug in the settings dialog that closed the dialog if the user canceled the save as dialog.
  • BUG FIX: Fixed problems with parsing FASTA files containing headers with empty sequences.
  • BUG FIX: Using a relative path for the database is now supported in the command line mode when creating the search parameters file.
  • LIBRARY UPDATE: Updated utilities to version 3.25.12.

New in SearchGUI 1.16.4 (Mar 7, 2014)

  • BUG FIX: Fixed a bug in the parsing of FASTA files with unknown headers.
  • BUG FIX: Fixed errors with the TMT 10-plex reporter ion masses.
  • LIBRARY UPDATE: Updated utilities to version 3.23.18

New in SearchGUI 1.16.2 (Feb 11, 2014)

  • BUG FIX: Fixed a backwards compatibility issue with the refinement modifications.
  • BUG FIX: Made the identification parameters mandatory when using the SearchGUI command line.
  • LIBRARY UPDATE: Updated utilities to version 3.21.31.

New in SearchGUI 1.16.1 (Feb 10, 2014)

  • BUG FIX: Fixed a memory issue occurring during the protein database loading for Mac and Linux.
  • BUG FIX: Fixed a bug in the command line where spectrum files where not closed and duplicated spectrum titles could not be corrected.
  • BUG FIX: Fixed a bug in the command line where the FASTA file was not set in the SearchCLIInputBean.
  • BUG FIX: Improved the command line test for duplicate titles to only fixing titles if there are titles to fix, and not always as before.
  • BUG FIX: If the search crashed in command line mode the JVM is now shut down.
  • LIBRARY UPDATE: Updated utilities to version 3.21.30.

New in SearchGUI 1.16.0 (Feb 5, 2014)

  • NEW FEATURE: Updated X!Tandem to version SLEDGEHAMMER (2013.09.01) for all platforms.
  • NEW FEATURE: The user can now decide how to handle duplicate spectrum titles: rename, remove or do nothing.
  • NEW FEATURE: The mgf files are now checked for peak picking (a simple zero intensity test) when loading.
  • NEW FEATURE: Added new auto update functionality of SearchGUI.
  • NEW FEATURE: Added the possibility to modify most search engine parameters, X!Tandem and OMSSA, from both the GUI and the command line.
  • NEW FEATURE: Added the possibility to create identification parameters files from the command line.
  • FEATURE IMPROVEMENT: GUI improvements to the SearchGUI main frame.
  • BUG FIX: Fixed a bug in the SpectrumFactory where one ended up with partial index files if the process was canceled by the user.
  • BUG FIX: Stopped the "PTM Definition Obsolete" error from occurring when it should not.
  • BUG FIX: Fixed bugs in the correction of duplicate spectrum titles.
  • BUG FIX: Fixed a backwards compatibility issues with the precursor accuracy in the search parameters.
  • LIBRARY UPDATE: Updated utilities to version 3.21.26.

New in SearchGUI 1.15.2 (Jan 10, 2014)

  • FEATURE IMPROVEMENT: The protein tree is now only created parallel with the searches if the provided memory is at least 4GB, to reduce the chance of memory issues occurring.
  • LIBRARY UPDATE: Updated utilities to version 3.20.3.

New in SearchGUI 1.15.1 (Jan 8, 2014)

  • NEW FEATURE: The user can now click the spectrum text field to see and edit the list of selected files.
  • FEATURE IMPROVEMENT: Re-added the Save As option in the Search Settings dialog.
  • FEATURE IMPROVEMENT: Refinement modifications in X!Tandem are now turned off whenever a conflict can occur with main modifications.
  • FEATURE IMPROVEMENT: Improved the handling of n-term acetylation and pyro modifications.
  • BUG FIX: Tried to fix a bug where canceling a search and then starting a second search resulted in the waiting dialog acting strange.
  • BUG FIX: The waiting dialog text report file format is now set as html.
  • LIBRARY UPDATE: Updated utilities to version 3.20.2.

New in SearchGUI 1.15.0 (Jan 3, 2014)

  • NEW FEATURE: The peptide to protein mapping needed in PeptideShaker is now generated parallel to the searches.
  • NEW FEATURE: Added command line support for FASTA file manipulation.
  • NEW FEATURE: The species can now be provided as input to SearchGUI (for use when reprocessing in PRIDE).
  • FEATURE IMPROVEMENT: Added better support for semi-specific enzymes.
  • FEATURE IMPROVEMENT: Cleaned up the help and about texts.
  • FEATURE IMPROVEMENT: Added tip of the day to the waiting dialog.
  • FEATURE IMPROVEMENT: The validation of the mgf files has been merged with the indexing of the files, instead of being two separate steps as before. And validation status is now saved in the file. Results in quicker validation that only has to be done once.
  • FEATURE IMPROVEMENT: Added a memory and Java version check to the PeptideShaker settings dialog.
  • FEATURE IMPROVEMENT: Got rid of the derby.log file.
  • FEATURE IMPROVEMENT: Removed .mgf from the default PRIDE project names, and added support for names with multiple files.
  • FEATURE IMPROVEMENT: The dialog asking the user if he/she wants to overwrite existing search result files is now only shown once (and not once per files as before).
  • FEATURE IMPROVEMENT: Removed the config file panel from the SearchSettings Dialog.
  • BUG FIX: Fixed a bug where choosing to not fix duplicated spectrum titles resulted in the mgf file not being selected.
  • BUG FIX: Made sure that only valid search parameter files can be selected.
  • BUG FIX: Fixed some bugs with editing the reporter and neutral ions in the Modification Details dialog.
  • BUG FIX: Fixed the X!Tandem enzyme formatting for the Whole Protein and Top Down enzymes.
  • BUG FIX: Fixed a bug in the parsing of sequence headers of type Generic_Split_Header.
  • BUG FIX: Fixed a bug with the handling of corrupt PRIDE PTM mapping files.
  • LIBRARY UPDATE: Updated utilities to version 3.19.5.

New in SearchGUI 1.14.4 (Aug 12, 2013)

  • LIBRARY UPDATE: Updated utilities to version 3.14.19.

New in SearchGUI 1.14.3 (Jul 15, 2013)

  • BUG FIX: Made the tool Java 6 compatible again.
  • LIBRARY UPDATE: Updated utilities to version 3.14.16.

New in SearchGUI 1.14.2 (Jul 10, 2013)

  • BUG FIX: Fixed a bug in the command line where the process got stopped before the searches could get started.
  • LIBRARY UPDATE: Updated utilities to version 3.14.14.

New in SearchGUI 1.14.1 (Jul 5, 2013)

  • NEW FEATURE: Extended the species support.
  • NEW FEATURE: Database details dialog.
  • BUG FIX: Fixed a bug in the Mac/Linux assembly that resulted in a corrupt jar file.
  • BUG FIX: Fixed a problem with the permissions on Mac/Linux.
  • LIBRARY UPDATE: Updated utilities to version 3.14.7.

New in SearchGUI 1.13.2 (May 14, 2013)

  • BUG FIX: Fixed a bug where white space was not allowed in the installation path.
  • LIBRARY UPDATE: Updated utilities to version 3.13.18.

New in SearchGUI 1.13.1 (May 13, 2013)

  • BUG FIX: Fixed a bug related to setting the OMSSA modification indexes when running SearchGUI from the command line.
  • LIBRARY UPDATE: Updated utilities to version 3.13.17.

New in SearchGUI 1.13.0 (May 12, 2013)

  • NEW FEATURE: Added MGF splitting options to the command line.
  • NEW FEATURE: The size of the MGF files is now also checked when using the PeptideShaker PRIDE Reshake feature.
  • FEATURE IMPROVEMENT: Tried to improve the error message displayed if the SearchGUI to PeptideShaker link fails.
  • FEATURE IMPROVEMENT: Added an extra test to check that the provided PeptideShaker path actually exists before starting the PeptideShaker processing.
  • FEATURE IMPROVEMENT: Only mgf files are now supported as spectrum file input, as this is the only format currently supported in PeptideShaker.
  • BUG FIX: Fixed a problem with starting the tool on the latest Java release.
  • BUG FIX: Fixed a bug in the SearchGUI command line where fixed modification was used instead of variable modification, making all PTMs fixed. (Only affected command lines where the PTMs were provided directly.)
  • BUG FIX: Fixed a bug that resulted in the PTMs not actually being used even when provided directly on the command line.
  • BUG FIX: Renamed the X!Tandem Linux binaries so that they can be auto detected.
  • BUG FIX: OMSSA PTM indexes are now set for all search parameters.
  • LIBRARY UPDATE: Updated utilities to version 3.13.16.

New in SearchGUI 1.12.2 (May 12, 2013)

  • BUG FIX: Fixed a problem with the renaming of X!Tandem files.
  • LIBRARY UPDATE: Updated utilities to version 3.11.29.

New in SearchGUI 1.12.1 (May 12, 2013)

  • FEATURE IMPROVEMENT: The search report now includes the search parameters, and is also created when ran from the command line (but then with just the search parameters).
  • BUG FIX: Fixed a bug that made it impossible to change the memory settings.
  • LIBRARY UPDATE: Updated utilities to version 3.11.27.

New in SearchGUI 1.12.0 (Mar 25, 2013)

  • NEW FEATURE: Added command line options for setting the search engine locations.
  • FEATURE IMPROVEMENT: Updated X!Tandem to version CYCLONE (2013.2.01) for all platforms.
  • FEATURE IMPROVEMENT: The SettingsDialog now tries to check if the search parameters have changed when the user clicks the OK button, and if any changes are detected ask the user if he/she wants to save the changes.
  • FEATURE IMPROVEMENT: Added a check for if the PeptideShaker jar file actually exists in the PeptideShakerSettingsDialog.
  • BUG FIX: Fixed a bug in the on/off settings for the search engines when run from the command line.
  • BUG FIX: Fixed some issues that occurred when opening SearchGUI with search parameters and/or mgf files.
  • BUG FIX: Fixed a bug in the check for new versions for SearchGUI that assumed that new versions for all operating systems were always released at the same time.
  • BUG FIX: Tried to fix a problem occurring with X!Tandem file names with regular expressions in them.
  • BUG FIX: Fixed minor code issues detected by FindBugs.
  • LIBRARY UPDATE: Excluded unused transitive dependency ssj.
  • LIBRARY UPDATE: Updated utilities to version 3.11.25.

New in SearchGUI 1.10.2 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: Minor fixes to make SearchGUI better compatible with PeptideShaker v0.18.0
  • BUG FIX: Fixed a path bug that occurred when running SearchGUI from PeptideShaker.
  • LIBRARY UPDATE: Updated utilities to version 3.8.6.

New in SearchGUI 1.10.1 (Sep 8, 2012)

  • NEW FEATURE: The selected output folder can now be created if it does not already exist.
  • FEATURE IMPROVEMENT: Added right click Edit popup menus for the tables in the modification tab.
  • BUG FIX: Fixed an issue with the indexing of the FASTA file when appending decoys.
  • BUG FIX: The mgf files are now re-indexed if needed.
  • LIBRARY UPDATE: Updated utilities to version 3.8.2.

New in SearchGUI 1.10.0 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: Dramatically reduced the time required to index and split files, and add decoys.
  • FEATURE IMPROVEMENT: Improved the canceling of searches, such that the actual search processes are now canceled if the user clicks the cancel button.
  • FEATURE IMPROVEMENT: Set the default splitting limit to 1000 MB, and 25000 spectra per MGF file.
  • FEATURE IMPROVEMENT: Replaced uses of "\n" with System.getProperty("line.separator").
  • LIBRARY UPDATE: Updated utilities to version 3.7.6.

New in SearchGUI 1.9.0 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: Double clicking in the defaults PTM table now brings up the PTM details.
  • FEATURE IMPROVEMENT: Added a test so that the user does not load different mgf files with the same name.
  • FEATURE IMPROVEMENT: Re-indexes the mgf files if the indexes do not contain precursor intensities.
  • FEATURE IMPROVEMENT: Re-added the database selection to the Settings tab.
  • FEATURE IMPROVEMENT: Improved the handling of errors in the user input.
  • FEATURE IMPROVEMENT: Improved the look and feel of the titled borders when using Java 7.
  • BUG FIX: Corrected a bug in the PTM jump to table feature.
  • BUG FIX: Fixed an issue in the ProgressDialogX that resulted in threading issues and deadlock on Java 7.
  • LIBRARY UPDATE: Updated utilities to version 3.6.10.

New in SearchGUI 1.8.9 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: The tool will now detect if the user tries to start it from within a zip file.
  • FEATURE IMPROVEMENT: Fixed the font color of the titled borders to look better when using Java 7.
  • BUG FIX: Made it possible to edit the user defined PTMs.
  • BUG FIX: The progress bars shown when adding decoy sequences and splitting mgf files are now working again.
  • LIBRARY UPDATE: Updated utilities to version 3.5.6.

New in SearchGUI 1.8.8 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: File shortcuts (lnk files) are now shown in the file selection dialogs.
  • BUG FIX: Corrected a bug in the handling of neutral losses.

New in SearchGUI 1.8.7 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: Increased the default size before the user is asked if he/she wants to split mgf files (> 2 0000 MB, > 25 000 000 spectra).
  • BUG FIX: Fixed a thread issue that could cause the GUI to hang.

New in SearchGUI 1.8.6 (Sep 8, 2012)

  • FEATURE IMPROVEMENT: Split the fragment ion types into forward (a,b,c) and backward (x,y,z) ions. (Such that the same ion type cannot be selected twice.)
  • LIBRARY UPDATE: Updated utilities to version 3.4.23.